Medicine composition for treating cervical spondylosis, and preparation method and application of medicine composition

A composition and technology for cervical spondylosis, applied in the field of medicine, can solve the problems of strong dependence on western medicine, strong toxic and side effects, and long course of treatment, and achieve the effect of overcoming slow onset of effect, overcoming toxic and side effects, and convenient administration

Active Publication Date: 2020-11-06
SHANDONG MINGREN FURUIDA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional Chinese medicine compound has problems such as slow onset of effect and long course of treatment in the treatment of cervical spondylosis, while Western medicine is highly dependent and often accompanied by strong toxic and side effects. One of the important subjects of research

Method used

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  • Medicine composition for treating cervical spondylosis, and preparation method and application of medicine composition
  • Medicine composition for treating cervical spondylosis, and preparation method and application of medicine composition
  • Medicine composition for treating cervical spondylosis, and preparation method and application of medicine composition

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Experimental program
Comparison scheme
Effect test

Embodiment

[0068] 1. Materials: Jingtong Granules are obtained from Shandong Mingren Freda Pharmaceutical Co., Ltd. (made from medicinal materials with the following weight ratio: 250 grams of Sanqi, 750 grams of Chuanxiong, 500 grams of Corydalis Corydalis, 1000 grams of Notopterygium, 750 grams of Paeoniae Alba , Clematis 1000 grams, Pueraria 750 grams); Levetiracetam and diclofenac sodium are commercially available.

[0069] 2. Animals: Wistar rats, weighing 180-220 g, provided by the Animal Experiment Center of Shandong University.

[0070] 3. Methods and results

[0071] The administration formula of each group of rats is shown in Table 1 below. The doses in Table 1 are the doses and volumes of a single administration, and the medicines are made into an equal volume of liquid with normal saline, and then intragastrically administered once a day for one week continuously. There were 6 rats in each group, half male and half male.

[0072] Table 1

[0073] group normal s...

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PUM

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Abstract

The invention provides a medicine composition for treating cervical spondylosis, and a preparation method and application of the medicine composition, and belongs to the technical field of medicine. Active ingredients of the medicine composition comprise the following two parts: (1) a traditional Chinese medicine active ingredient prepared from following traditional Chinese medicinal materials inparts by weight: 1 to 15 parts of radix notoginseng, 3 to 20 parts of rhizoma chuanxiong, 2 to 15 parts of rhizoma corydalis, 3 to 20 parts of radix paeoniae alba, 4 to 25 parts of radix clematidis, 3to 20 parts of radix puerariae and 4 to 25 parts of notopterygium roots; and (2) a western medicine active ingredient prepared from levetiracetam and diclofenac sodium according to a weight ratio of1:(1 to 4). The medicine composition for treating cervical spondylosis provided by the invention is medicine integrating traditional Chinese medicine and western medicine developed on the basis of Chinese patent CN1228071C, has the unique curative effect on treatment of cervical spondylosis, and has the advantages that the preparation process is simple; the curative effect is obvious; the effect taking time is short; the taking is convenient; no toxic and side effects exist; and safety and effectiveness are realized.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating cervical spondylosis, a preparation method and application thereof. Background technique [0002] The information disclosed in this background section is only intended to increase the understanding of the general background of the present invention, and is not necessarily taken as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to those skilled in the art. [0003] Cervical spondylotic radiculopathy is a common and frequently-occurring disease in the Department of Orthopedics and Traumatology, and it is also the most common type of cervical spondylosis, accounting for about 60-70% of the incidence. The earliest concepts of cervical spondylosis in modern medicine are mostly derived from cervical spondylosis of the nerve root type. It not only has a high incidence rate, b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/716A61P19/00A61K31/4015A61K31/196
CPCA61K36/258A61K36/236A61K36/66A61K36/71A61K36/65A61K36/716A61K36/488A61K36/237A61K31/4015A61K31/196A61P19/00A61K2236/331A61K2236/39A61K2236/333A61K2236/51A61K2300/00Y02A50/30
Inventor 刘杰张亚欣郝红慧陈克欣江玉娟许敏高超潘瑞雪王莉
Owner SHANDONG MINGREN FURUIDA PHARMA
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