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Breast cancer lesion image segmentation method based on an end-to-end neural network

A neural network and neural network model technology, applied in the field of breast cancer lesion segmentation based on end-to-end neural network, can solve the problems of inaccurate edge position, poor segmentation effect, and unclear boundary of edge segmentation, etc., and achieve good learning characteristics , the segmentation effect is good, and the effect of reducing the imbalance between positive and negative samples

Inactive Publication Date: 2020-11-10
NANTONG UNIVERSITY
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AI Technical Summary

Problems solved by technology

From the experimental comparison results, it is found that these algorithms still have some problems in the segmentation of the edge of breast cancer lesions. The boundary of edge segmentation is not clear enough, the segmentation effect of the edge soft tissue with similar gray level is not good, and the edge position is not accurate enough.

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  • Breast cancer lesion image segmentation method based on an end-to-end neural network
  • Breast cancer lesion image segmentation method based on an end-to-end neural network
  • Breast cancer lesion image segmentation method based on an end-to-end neural network

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Experimental program
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Effect test

Embodiment

[0034] 1. Manual labeling

[0035] The data used in the experiment of the present invention are all real data obtained by the MR imaging department of the hospital during the diagnosis and treatment of breast cancer, and are used for the experiment under the authorization of the hospital. The data of this experiment mainly collected 50 patients, and each patient included images of four different stages: 1st stage, 2nd stage, 4th stage and 6th stage. The software used for the experimental labeling of the present invention is ITK-SNAP, which is used to manually mark the lesion area layer by layer, and save it as a marked file separately. A pixel with a pixel value of 1 in the file represents the lesion area, and a pixel with a pixel value of 0 represents the background area. This markup file corresponds to the original image in preparation for subsequent processing.

[0036] 2. Data preprocessing

[0037] Since the 3D image data obtained from the hospital is relatively large,...

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Abstract

The invention discloses a breast cancer lesion image segmentation method based on an end-to-end neural network. The breast cancer lesion image segmentation method comprises the following steps: step 1, labeling by hands: marking a lesion area on data according to experience of a doctor; step 2, preprocessing data: preprocessing the three-dimensional image data, and cutting the three-dimensional image data into an image size suitable for a neural network; step 3, selecting a model: selecting an improved end-to-end neural network model; step 4, training a model: training an optimal model on themarked training set by using an improved network model; step 5, predicting data: predicting a focus area by using the trained model; and step 6, evaluating a result: measuring the accuracy of focus segmentation by utilizing corresponding evaluation indexes. According to the improved end-to-end neural network provided by the invention, a hole residual network is used on an original resolution image, and rich feature information of a target is maintained; and a Dice loss function in a weighted form is also adopted, so that the segmentation effect on a small target and a lesion edge region is better.

Description

technical field [0001] The invention specifically relates to a method for segmenting images of breast cancer lesions based on an improved end-to-end neural network model. Background technique [0002] According to the relevant data of the World Health Organization, breast cancer has become the cancer with the highest incidence rate in women, seriously endangering women's health. In order to be able to reduce the mortality rate of breast cancer, early diagnosis and treatment are needed. [0003] With the continuous development of neural networks, three-dimensional convolutional neural networks have begun to emerge, which make full use of the inter-layer correlation of three-dimensional images, and have been better applied in the processing of 3D medical images. With the continuous development of deep learning, there are already some segmentation algorithm models for processing 3D images, such as 3D-Unet and V-Net. The two 3D segmentation algorithm models contain the prototy...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/00G06T7/11G06N3/04
CPCG06T7/0012G06T7/11G06T2207/20081G06T2207/20084G06T2207/30068G06T2207/30096G06N3/045
Inventor 邵叶秦高瞻汤卫霞汤佳欢盛美红
Owner NANTONG UNIVERSITY