Composition with synergistic tyrosinase inhibition effect and application thereof
A technology of tyrosinase and synergistic inhibition is applied in the directions of drug combination, active ingredients of hydroxyl compounds, and medical preparations containing active ingredients, etc., which can solve the problems of high cost, unsatisfactory effect and high cost, and achieve the effect of reducing dosage.
Pending Publication Date: 2020-11-13
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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- Abstract
- Description
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Problems solved by technology
There are many treatment techniques and anti-freckle products for chloasma, most of which are expensive and expensive; but the curative effect is not satisfactory, and almost all of them are accompanied by adverse reactions
Both resveratrol and phenylethylresorcinol have antioxidant and tyrosinase-inhibiting effects, but there is no research report on combining the two into a composition to inhibit tyrosinase
Method used
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Embodiment 1
[0012] A composition with a synergistic inhibitory effect on tyrosinase consists of resveratrol and phenylethylresorcinol at a molar ratio of 30.
Embodiment 2
[0014] A composition with synergistic inhibitory effect on tyrosinase consists of resveratrol and phenylethylresorcinol in a molar ratio of 10.
Embodiment 3
[0016] A composition with a synergistic inhibitory effect on tyrosinase is composed of resveratrol and phenylethylresorcinol in a molar ratio of 8.
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Abstract
The invention discloses a composition with a tyrosinase inhibiting effect and an application thereof. The composition is prepared from resveratrol and phenethyl resorcinol according to the molar massratio of 0.03 to 30. Experiments prove that the composition disclosed by the invention has the effect of synergistically inhibiting tyrosinase, and can be used for treating chloasma, erythema after acne, freckles and senile plaques, repairing after sun exposure and resisting oxidation.
Description
technical field [0001] The invention relates to a composition with antioxidant activity, in particular to a composition and application with synergistic inhibition of tyrosinase. Background technique [0002] Chloasma is the most common melanosis disease, mostly occurs in the exposed parts of the face of young and middle-aged women, affects the appearance, and is difficult to treat at the same time. It is a major disease problem that is difficult to solve in the medical field. Its characteristics are: the onset is affected by many factors (ultraviolet stimulation, inflammatory response, etc.), stubborn, and easy to relapse. There are many treatment techniques and freckle products for chloasma, most of which are expensive and expensive; but the curative effect is unsatisfactory, and almost all of them are accompanied by adverse reactions. Both resveratrol and phenylethylresorcinol have antioxidant and tyrosinase-inhibiting effects, but there is no research report on combinin...
Claims
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Patent Timeline

IPC IPC(8): A61K31/05A61K8/34A61Q19/08A61Q19/00A61P17/16A61P17/18A61P17/00A61P17/10
CPCA61K8/347A61K31/05A61K2800/5922A61K2800/782A61Q19/004A61Q19/08A61P17/00A61P17/10A61P17/16A61P17/18A61K2300/00
Inventor 靳佳慧王艳刘轩鸣
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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