New coronavirus RBD specific monoclonal antibody and application
A monoclonal antibody and specific technology, applied in the direction of antibodies, applications, antiviral agents, etc., can solve the problem of limited virus blocking effect, achieve the effect of improving specific binding ability and wide application value
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Example Embodiment
[0020] Example 1
[0021] The present embodiment provides a new crown RBD virus specific monoclonal antibodies, the heavy chain amino acid sequence as SEQ IDNO: 1 shown; light chain amino acid sequence set forth in SEQ ID NO: 2 shown in FIG.
[0022] The present embodiment further provides the above novel crown RBD virus specific monoclonal antibodies, in the manufacture of diagnostic or detection of SARS-CoV-2 agent or medicament.
[0023] In actual production, the pharmaceutical compositions according to the present embodiment, a nucleic acid molecule to give a monoclonal antibody preparation specific RBD, or preparing the expression cassette comprising the nucleic acid molecule, recombinant vector, recombinant bacteria or transgenic cell lines, or a pharmaceutical composition, may be employed It includes the above novel crown RBD virus specific monoclonal antibodies and a pharmaceutically acceptable excipient, diluent or carrier.
[0024] In use, the present embodiment to obtai...
Example Embodiment
[0025] Example 2-20
[0026] Example 2-20 distinction of Example 1 in that: RBD different amino acid sequence specificity of monoclonal antibodies, the amino acid sequence of Example 2-20 shown in the following table:
[0027] test group Heavy chain amino acid sequence Light chain amino acid sequence Example 1-CQT149 SEQ ID NO: 1 SEQ ID NO: 2 Example 2-CQT190 SEQ ID NO: 3 SEQ ID NO: 4 Example 3-CQT191 SEQ ID NO: 5 SEQ ID NO: 6 Example 4-CQT195 SEQ ID NO: 7 SEQ ID NO: 8 Example 5-CQT197 SEQ ID NO: 9 SEQ ID NO: 10 Example 6-CQT198 SEQ ID NO: 11 SEQ ID NO: 12 Example 7-CQT199 SEQ ID NO: 13 SEQ ID NO: 14 Example 8-CQT200 SEQ ID NO: 15 SEQ ID NO: 16 Example 9-CQT201 SEQ ID NO: 17 SEQ ID NO: 18 Example 10-CQT201 SEQ ID NO: 19 SEQ ID NO: 20 Example 11-CQT202 SEQ ID NO: 21 SEQ ID NO: 22 Example 12-CQT203 SEQ ID NO: 23 SEQ ID NO: 24 Example 13-CQT206 SEQ ID NO: 25 SEQ ID NO: 26 Example 14-CQT209 S...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap