Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A composition for skin barrier repair and its preparation method

A skin barrier repair and composition technology, which is applied in the fields of biomedicine and personal care products, can solve problems such as skin irritation, and achieve the effects of improving eczema, smooth skin, and reducing irritation.

Active Publication Date: 2022-04-19
BLOOMAGE BIOTECHNOLOGY CORP LTD
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing emollients that claim to have the effect of repairing the skin barrier all use more or less emulsifiers, preservatives, or additives with antiseptic effects, which are irritating to the skin

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A composition for skin barrier repair and its preparation method
  • A composition for skin barrier repair and its preparation method
  • A composition for skin barrier repair and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0072] In a specific embodiment of the present application, the preparation method of the water-based composition comprises the following steps:

[0073] In a clean environment above 300,000 degrees, add the hyaluronic acid or its salt, glycerin, and allantoin into water at about 85°C, stir to dissolve evenly, and add Bacillus / soybean fermentation and extraction when the temperature drops to about 50°C liquid, α-glucan oligosaccharides, inulin, and stirred evenly to obtain a water-based composition.

[0074] The present application also relates to the use of the water-based composition and the oil-based composition for skin barrier repair. The components of the water-based composition and the oil-based composition provided in the present application are all non-animal source materials, and have good biosafety and biocompatibility. This application, through the scientific combination of hyaluronic acid or its salts with different molecular weights and other multiple ingredient...

Embodiment 1

[0082] Prepare the water-based composition and the oil-based composition according to the following proportions and methods:

[0083] Water-based composition: sodium hyaluronate with a molecular weight of 5000 Da: 0.3 g; sodium hyaluronate with a molecular weight of 290,000 Da: 0.3 g; sodium hyaluronate with a molecular weight of 780,000 Da: 0.1 g; Sodium hyaluronate: 0.1g; Sodium hyaluronate cross-linked polymer 5g; Bacillus / soybean fermentation extract: 5g; α-glucan oligosaccharide: 1g; Inulin: 1g; Allantoin: 0.2g; Glycerin: 5g; water 82g.

[0084] In a clean environment above 300,000 degrees, add the hyaluronic acid or its salt, glycerin, and allantoin into water at about 85°C, stir to dissolve evenly, and add Bacillus / soybean fermentation and extraction when the temperature drops to about 50°C liquid, α-glucan oligosaccharides, inulin, and stirred evenly to obtain a water-based composition.

[0085] Oil-based composition: 40 g of squalane; 13 g of white pond flower seed ...

Embodiment 2

[0089] Prepare water-based composition and oil-based composition according to the following proportions:

[0090] Water-based composition: sodium hyaluronate with a molecular weight of 9000 Da: 0.1 g; sodium hyaluronate with a molecular weight of 290,000 Da: 0.1 g; sodium hyaluronate with a molecular weight of 780,000 Da: 0.05 g; Sodium hyaluronate: 0.05g; Sodium hyaluronate cross-linked polymer 3g; Bacillus / soybean fermentation extract: 3g; α-glucan oligosaccharide: 0.5g; Inulin: 0.5g; Allantoin: 0.2 g; glycerin: 5g; water 87.5g.

[0091] In a clean environment above 300,000 degrees, add the hyaluronic acid or its salt, glycerin, and allantoin into water at about 85°C, stir to dissolve evenly, and add Bacillus / soybean fermentation and extraction when the temperature drops to about 50°C liquid, α-glucan oligosaccharides, inulin, and stirred evenly to obtain a water-based composition.

[0092] Oil-based composition: 40 g of squalane; 13 g of white pond flower seed oil; 5 g of...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
molecular weightaaaaaaaaaa
Login to View More

Abstract

The present application discloses a skin barrier repair composition and its preparation method, the main components of which include hyaluronic acid or its salt, Bacillus / soybean fermentation extract, allantoin, α-glucan oligosaccharides, inulin, Glycerin, squalane, and white pool flower seed oil are divided into water and oil and packaged separately, avoiding the addition of preservatives, emulsifiers, flavors and other ingredients. The composition can form a film on the skin surface, reduce skin water loss while isolating external pollution, increase skin water content, and have super moisturizing and repairing effects on the skin epidermis, stratum corneum and skin on the skin surface. At the same time, the composition is beneficial to maintain the normal microbial environment on the skin surface, improve various skin problems such as eczema and dermatitis caused by microbial imbalance caused by the harsh skin surface environment, and is beneficial to skin eczema, sweat rash, baby diaper rash, perianal eczema, skin rash, etc. Ringworm, etc. have a particularly pronounced effect.

Description

technical field [0001] The invention relates to the technical fields of biomedicine and personal care products, in particular to a skin barrier repairing composition and a preparation method thereof. Background technique [0002] Skin barrier, in a broad sense, includes physical barrier, pigment barrier, nerve barrier, and immune barrier. The skin barrier in the narrow sense mainly refers to the physical barrier of the skin. The skin barrier we usually refer to refers to the physical barrier of the skin. The physical barrier of the skin is composed of sebum membrane, stratum corneum keratin, lipid, "sandwich" structure, brick wall structure, dermal mucopolysaccharides, mucopolysaccharides, etc., to resist external harmful substances, irritants, and sunlight. , while moisturizing and regulating anti-inflammatory effects. [0003] In recent years, the environment has continued to deteriorate, bacteria and viruses have grown in large numbers, and people's skin is exposed to t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/99A61K36/48A61K8/34A61K8/49A61K8/73A61K8/92A61K8/9789A61K8/31A61P17/00A61P29/00A61P31/02A61P31/04A61K31/01A61K31/047A61K31/4166A61K31/716A61K31/728A61K31/733A61K35/742
CPCA61K31/728A61K36/48A61K31/4166A61K31/716A61K31/733A61K31/047A61K31/01A61K36/185A61K36/23A61P17/00A61P29/00A61P31/02A61P31/04A61K8/736A61K8/9789A61K8/4946A61K8/735A61K8/73A61K8/345A61K8/31A61K8/922A61K8/99A61Q19/00A61Q17/005A61K35/742A61K2236/19A61K2800/30A61K2800/5922A61K2300/00
Inventor 申凤同董建军李杰毛华李锋陈柏秀阚洪玲郭学平
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com