Orthopedic composite adhesive material and preparation method thereof

An adhesive material and orthopedic technology, applied in the field of medical materials, can solve the problems of poor antibacterial performance and achieve the effect of enhanced antibacterial performance, high biological safety, and excellent antibacterial performance

Active Publication Date: 2021-01-22
合肥中科智远生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is that the existing orthopedic composite adhesive materials release a large amount of heat during polymerization and have poor antibacterial properties.

Method used

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  • Orthopedic composite adhesive material and preparation method thereof
  • Orthopedic composite adhesive material and preparation method thereof
  • Orthopedic composite adhesive material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] The orthopedic composite adhesive material includes a solid component and a liquid component, and the mass ratio of the solid component to the liquid component is 2:1. Solid components include 16.2g polymethyl methacrylate (90wt%), 1.8g furyl aromatic polyamide powder (10wt%), 2g barium sulfate (BaSO 4), 0.1g benzoyl peroxide (BPO); liquid components include 10mL methyl methacrylate, 50uL N,N-dimethyl-p-toluidine (Dmpt), furyl aromatic polyamide powder used in this embodiment The publication number is the high molecular weight furan-based polyamide in Example 1 of the patent application specification CN110256668A. Among them, barium sulfate is used as a contrast agent, which plays a contrasting role, and benzoyl peroxide belongs to an initiator, which is used to initiate a second polymerization reaction during use. N,N-Dimethyl-p-toluidine catalyzes BPO to generate free radicals, which belongs to the activator. The molecular weight of polymethyl methacrylate in this e...

Embodiment 2

[0051] The difference between this example and Example 1 is that the mass of polymethylmethacrylate is 17.1g (95wt%), and the mass of furyl aromatic polyamide powder is 0.9g (0.05wt%).

[0052] At a temperature of 23°C and a humidity of 40%, it was left to stand for 3 minutes and then cured for 10 minutes to obtain a bioactive and antibacterial orthopedic medical composite adhesive material.

Embodiment 3

[0054] The difference between this example and Example 1 is that: the orthopedic medical composite adhesive material with bioactivity and antibacterial properties was obtained after standing for 3 minutes at a temperature of 21° C. and a humidity of 60% and then cured for 15 minutes.

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Abstract

The invention discloses an orthopedic composite adhesive material, and relates to the technical field of medical materials. The orthopedic composite adhesive material comprises a solid component and aliquid component, wherein the solid component comprises polymethyl methacrylate, furyl aromatic polyamide, a contrast agent and an initiator; and the liquid component comprises methyl methacrylate. The invention further provides a preparation method of the orthopedic composite adhesive material. The orthopedic composite adhesive material has the beneficial effects that a certain proportion of furyl aromatic polyamide material is mixed into the raw materials of the orthopedic medical composite adhesive material, and the orthopedic composite adhesive material belongs to a bio-based material, ishigh in biological safety, has relatively good biological activity, can effectively reduce thermal injury of tissues, has the heat release temperature of lower than 60 DEG C, and has excellent antibacterial performance.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to an orthopedic composite adhesive material and a preparation method thereof. Background technique [0002] Acrylic resin bonding materials have been used in orthopedics for more than 50 years. Conventional polymethyl methacrylate (PMMA) bonding materials include a powder (PMMA powder, developer, catalyst, and some contain colorants and antibiotic ingredients) and a liquid agent (MMA, accelerator, polymerization inhibitor, some containing coloring agent), the powder and liquid agent are mixed and stirred during use, and then the orthopedic adhesive material is delivered or introduced to the required part through the device, and the mixture passes through After the porridge stage, sticky silk stage, dough stage, and curing stage, it can be solidified and shaped, and it can play the role of bone filling and joint prosthesis fixation. [0003] PMMA adhesive material is the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/06A61L24/00A61L24/02A61L24/04
CPCA61L24/06A61L24/0015A61L24/001A61L24/02A61L24/046A61L2300/404A61L2300/216C08L33/12C08L77/06
Inventor 李闯傅尧
Owner 合肥中科智远生物科技有限公司
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