16S and metagenome sequencing data association analysis method and system, and equipment

A technology of association analysis and metagenomic, applied in the field of data processing and analysis, to achieve the effect of complementing each other
CN112669899AActive Publication Date: 2021-04-16GUANGZHOU GENE DENOVO BIOTECH
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Patent Information

Authority / Receiving Office
CN Β· China
Current Assignee / Owner
GUANGZHOU GENE DENOVO BIOTECH
Publication Date
2021-04-16

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Abstract

The invention relates to a 16S and metagenome sequencing data association analysis method and system, and equipment. According to the scheme, the method comprises the following steps: performing 16S sequencing and metagenomics sequencing on a sample to obtain 16S omics data and metagenomics data; carrying out microPITA analysis according to the 16S omics data to obtain a representative sample; performing Ween analysis according to the 16S omics data and the metagenomics data to obtain common and specific statistical species / function statistics, and performing graphical display; carrying out species / function distribution analysis to obtain species / function abundance changes and main species / function types in all the samples of the two omics; and performing correlation analysis and environmental factor correlation analysis according to the 16S omics data and the metagenomics data. According to the scheme, the 16S and metagenome sequencing data correlation analysis method is provided, the metagenome extension data is used for researching the depth, 16S is used for verifying the analysis accuracy of metagenome data, and mutual complementation and verification of two omics data are achieved.
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Description

technical field

[0001] The present invention relates to the field of data processing and analysis, in particular to a method, system and equipment for correlation analysis of 16S and metagenomic sequencing data. Background technique

[0002] Microorganisms are closely related to biology, environment, production and other aspects, and play an important role. Among them, human microorganisms are considered as the second genome of human beings. With the development of science and technology, high-throughput sequencing is also becoming more and more popular. 16S sequencing technology and metagenomic sequencing technology are two important high-throughput sequencing methods. 16S sequencing technology generally only focuses on the study of community diversity changes, while metagenomic sequencing focuses on mining the functional structure of microbial communities.

[0003] The existing technology has the following defects: although the 16S sequencing data can be used to analyze ...

Claims

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