A traditional Chinese medicine active ingredient composition for the treatment of postmenopausal osteoporosis and its application

A technology for osteoporosis and active ingredients, applied in the field of medicine, can solve the problems of carrying, inconvenient taking, unclear ingredients, etc., and achieve the effect of rich raw materials, high economic and social benefits, and convenient preparation methods

Active Publication Date: 2022-08-09
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Treatment should be based on tonifying the kidney, strengthening the bones, and activating blood circulation. Many traditional Chinese medicine prescriptions are used in the treatment, but there are deficiencies such as carrying, inconvenient taking, and unclear ingredients.

Method used

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  • A traditional Chinese medicine active ingredient composition for the treatment of postmenopausal osteoporosis and its application
  • A traditional Chinese medicine active ingredient composition for the treatment of postmenopausal osteoporosis and its application
  • A traditional Chinese medicine active ingredient composition for the treatment of postmenopausal osteoporosis and its application

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Effect test

Embodiment 1

[0039] In the specific implementation of the present invention, the active ingredient of the traditional Chinese medicine of the present invention is composed of 50 mg of Lycium barbarum polysaccharide, 6 mg of icariin, 50 mg of Polygonin, 1 mg of quercetin, and 10 mg of Danshensu sodium.

Embodiment 2

[0041] In the specific implementation of the present invention, the active ingredient formula of the traditional Chinese medicine of the present invention is composed of 350 mg of Lycium barbarum polysaccharide, 50 mg of icariin, 180 mg of Polygonin, 10 mg of quercetin, and 100 mg of Danshensu sodium.

Embodiment 3

[0043]In the specific implementation of the present invention, the active ingredient formula of the traditional Chinese medicine of the present invention is composed of 200 mg of Lycium barbarum polysaccharide, 30 mg of icariin, 120 mg of Polygoside, 5 mg of quercetin, and 60 mg of Danshensu sodium.

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Abstract

The invention provides a traditional Chinese medicine active ingredient composition for treating postmenopausal osteoporosis and application thereof, belonging to the field of medicine. Described traditional Chinese medicine active ingredient formula comprises Chinese medicinal active ingredient Lycium barbarum calculated by weight (mg) ratio (50~350):(6~100):(50~180):(1~10):(10~100) Polysaccharide, Icariin, Polygonin, Quercetin, Danshensu Sodium. The traditional Chinese medicine active ingredient composition of the invention has reasonable compatibility, complements each other, has exact curative effect and strong innovation, and can be effectively applied to the treatment of postmenopausal osteoporosis. After repeated verification, the composition can significantly improve postmenopausal osteoporosis. The model animal has bone mineral density, improves bone microstructure, is safe and effective, and can be used as a long-term drug for postmenopausal osteoporosis. The traditional Chinese medicine composition can be further prepared into a pharmaceutical preparation, the dosage form is small, it is convenient to carry and take, can obtain better economic and social benefits, and has broad application prospects.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to a traditional Chinese medicine active ingredient composition for treating postmenopausal osteoporosis and its application. Background technique [0002] Postmenopausal osteoporosis is a public health problem that seriously threatens the health of middle-aged and elderly people, with an estimated 200 million patients worldwide. Among women over 60 years old in my country, the prevalence of osteoporosis is as high as 40% to 50%, of which about 30% to 50% will experience osteoporosis-related fractures, which will seriously affect the health of the elderly and quality of life, resulting in a shortened lifespan. In my country, according to statistics, there are more than 90 million patients with osteoporosis and related fractures, and the annual medical expenses exceed 25 billion yuan, which seriously increases the financial and human burden of the country and families ("Osteoporosis China Whi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61K31/7048A61K31/05A61K31/352A61K31/192A61P19/10A61P15/12
CPCA61K31/715A61K31/7048A61K31/05A61K31/352A61K31/192A61P19/10A61P15/12A61K2300/00
Inventor 朱晓峰张荣华杨丽孙珂焕梅雯惠辛灵崔琰
Owner JINAN UNIVERSITY
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