Artemisia integrifolia and glossy ganoderma compound active extract, and preparation and preparation method thereof

An extract and technology of Ganoderma lucidum, applied in the field of artemisia annua and Ganoderma lucidum compound active extract and its preparation and preparation, can solve the problems of not using anti-diabetic and hypoglycemic drugs, and achieve excellent therapeutic effect, simple operation, mild and long-lasting effect Effect

Inactive Publication Date: 2021-06-18
通化鑫业生物科技研发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, there is no anti-diabetic and hypoglycemic drug using the compound active extract of Artemisia annua and Ganoderma lucidum as active ingredients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A pharmaceutical composition for treating diabetes, said pharmaceutical composition for treating diabetes comprises the following raw material components in parts by weight:

[0027] 1,000 parts of the composite active extract of Artemisia annua and Ganoderma lucidum, and 120 parts of auxiliary materials. The auxiliary materials are composed of raw materials in the following ratios by weight: starch:talcum powder:magnesium stearate=10:1:1.

[0028] The preparation method of the described Artemisia annua and Ganoderma lucidum composite active extract, the steps are as follows:

[0029] S1. Screen high-quality fresh Artemisia annua and Ganoderma lucidum, select the above-ground parts, wash, dry, and pulverize to obtain mixed scraps, add distilled water therein, grind and centrifuge with a colloid mill, and obtain a water-extracted centrifuge;

[0030] S2. Separating the water-extracted centrifugate through a macroporous resin to obtain an eluent;

[0031] S3. Concentrati...

Embodiment 2

[0041] A pharmaceutical composition for treating diabetes, said pharmaceutical composition for treating diabetes comprises the following raw material components in parts by weight:

[0042] Artemisia annua and Ganoderma lucidum compound active extract 1000 parts, auxiliary material 100 parts, described auxiliary material is starch.

[0043] The preparation method of the described Artemisia annua and Ganoderma lucidum composite active extract, the steps are as follows:

[0044] S1. Screen high-quality fresh Artemisia annua and Ganoderma lucidum, select the above-ground parts, wash, dry, and pulverize to obtain mixed scraps, add distilled water therein, grind and centrifuge with a colloid mill, and obtain a water-extracted centrifuge;

[0045]S2. Separating the water-extracted centrifugate through a macroporous resin to obtain an eluent;

[0046] S3. Concentrating the eluent under reduced pressure to obtain a concentrated solution;

[0047] S4. Vacuum freeze-drying the concent...

Embodiment 3

[0056] A pharmaceutical composition for treating diabetes, said pharmaceutical composition for treating diabetes comprises the following raw material components in parts by weight:

[0057] Artemisia annua and Ganoderma lucidum compound active extract 1000 parts, auxiliary material 100 parts, described auxiliary material is microcrystalline cellulose.

[0058] The preparation method of the described Artemisia annua and Ganoderma lucidum composite active extract, the steps are as follows:

[0059] S1. Screen high-quality fresh Artemisia annua and Ganoderma lucidum, select the above-ground parts, wash, dry, and pulverize to obtain mixed scraps, add distilled water therein, grind and centrifuge with a colloid mill, and obtain a water-extracted centrifuge;

[0060] S2. Separating the water-extracted centrifugate through a macroporous resin to obtain an eluent;

[0061] S3. Concentrating the eluent under reduced pressure to obtain a concentrated solution;

[0062] S4. Vacuum free...

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PUM

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Abstract

The invention discloses an artemisia integrifolia and glossy ganoderma compound active extract, and a preparation and a preparation method thereof, and relates to the technical field of drugs for treating diabetes. The preparation method includes the following steps: S1, screening high-quality and fresh artemisia integrifolia and glossy ganoderma, selecting aerial parts, performing cleaning, drying and crushing, obtaining a mixed crushed material, adding distilled water, performing grinding and centrifugation with a colloidal mill, and preparing water extraction centrifugate; S2, performing separation on the water extraction centrifugate through macroporous resin to obtain eluant; S3, performing vacuum concentration on the eluant to obtain concentrate; and S4, performing vacuum freeze drying on the concentrate to obtain the artemisia integrifolia and glossy ganoderma compound active extract.

Description

technical field [0001] The invention relates to the technical field of medicines for treating diabetes, in particular to a composite active extract of Artemisia annua and Ganoderma lucidum and its preparation and preparation method. Background technique [0002] Diabetes mellitus is an endocrine and metabolic disease characterized by absolute or relative deficiency of insulin secretion and disturbance of glucose metabolism. Chronic diseases can even cause blindness and disability, seriously affecting health, work and living ability. The occurrence and development of diabetes is a slow and hidden process. If elevated blood sugar is detected early and timely preventive treatment is carried out, the continued development of diabetes can be controlled from the source. [0003] At present, most clinical drugs used to treat diabetes are chemical drugs, which may cause side effects such as hypoglycemia and lactic acidosis, and long-term use will cause damage to the body. There is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61P3/10A61K36/074
CPCA61K36/28A61K36/074A61P3/10A61K2236/331A61K2236/55A61K2236/51A61K2300/00
Inventor 徐从立张家秋
Owner 通化鑫业生物科技研发有限公司
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