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Nanoemulsion based on ethoxylated fatty ether or ethoxylated fatty ester, and use thereof

An ethoxylation and nanotechnology, applied in the field of nanoemulsions, can solve problems such as adhesion

Inactive Publication Date: 2003-12-10
LOREAL SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these nanoemulsions have the disadvantage of being sticky when applied to the skin

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] A transparent nanoemulsion was obtained with a droplet size of 47 nm and a turbidity of 222 NTU. Example 2: Fragrance (scented water) oil phase for human body: - Nikkol BB10 (Nikko company) 4.5% - N-stearyl-L-glutamic acid disodium salt (0.5% acyl glutamic acid from Ajinomoto company Acid acid HS21) - soybean oil (molecular weight 900) 8.5% - volatile silicone oil (molecular weight = 106) 3% - fragrance 3% - vitamin E acetate 0.5% - ethanol 12.5% ​​water phase: glycerin 5% water to 100%

Embodiment 2

[0055] A transparent nanoemulsion was obtained with a droplet size of 42 nm and a turbidity of 149 NTU.

Embodiment 3

[0056] Example 3: Conditioner oil phase: - Compritol HD5 ATO (Gattefosse company) 4% - Behenyltrimethylammonium chloride 1% - Avocado oil (molecular weight 900) 15% - Ethanol 20% aqueous phase : - Glycerin 5% - Water qs to 100%

[0057] A transparent nanoemulsion with a droplet size of 55 nm and a turbidity of 230 NTU was obtained.

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PUM

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Abstract

A nanoemulsion comprising a dispersed lipid phase in an aqueous phase with lipid globules having an average size of less than 100 nm contains: (1) a surfactant such as ethoxylated fatty esters or ethers; and (2) at least one oil with a molecular weight of more than 400 and at a lipid phase / surfactant weight ratio of 2-10. Independent claims are also included for: (1) a topical composition comprising the above described composition; (2) an ophthalmic support comprising the above described composition; (3) a pharmaceutical composition comprising the above described composition; (4) a cosmetic method for the care and / or hydration of the skin, mucosa and / or scalp by applying the above described composition; and (5) the preparation of the composition by mixing an aqueous phase and a lipid phase at 10-80 degrees C and homogenizing the mixture at 6 x 10<7>-18 x 10<7> Pa.

Description

technical field [0001] The present invention relates to surfactants based on solids at lower than or equal to 45°C selected from ethoxylated fatty ethers or ethoxylated fatty esters and based on at least one oil with a molecular weight greater than 400 and the weight of the oil phase to the weight of the surfactant Nanoemulsions having a weight ratio in the range of 2 to 10. [0002] The invention also relates to a process for the preparation of said nanoemulsion and to its use in the field of cosmetology, dermatology and / or ophthalmology. The nanoemulsions are stable on storage and can include large amounts of oil while maintaining good clarity and having good cosmetic properties. Background technique [0003] Nanoemulsions are oil-in-water emulsions whose oil droplets are of very fine particle size. That is, the number average size is less than 100 nm. They are usually prepared by a process of mechanical disintegration of an oil phase in an aqueous phase in the presence...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/107A61K8/00A61K8/06A61K8/30A61K8/31A61K8/34A61K8/37A61K8/39A61K8/40A61K8/41A61K8/42A61K8/44A61K8/46A61K8/55A61K8/58A61K8/60A61K8/63A61K8/89A61K8/891A61K8/92A61K8/97A61K8/98A61K9/00A61K47/08A61K47/24A61K47/28A61K47/44A61P17/00A61P27/02A61Q1/00A61Q1/02A61Q1/10A61Q1/14A61Q5/00A61Q13/00A61Q19/00C09K23/00C09K23/42
CPCB01F17/0021A61K9/0048A61K8/06Y10S514/937A61Q5/00A61K2800/21B82Y5/00Y10S514/845A61K9/1075A61Q19/00Y10S514/844A61Q19/007A61Q1/14A61K2800/413Y10S514/938A61K2800/262A61P17/00A61P27/02C09K23/34C09K23/42
Inventor J·-T·西蒙尼特O·松尼维勒S·勒格雷特
Owner LOREAL SA
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