Rapid detection device for intestinal release of coated sustained-release product

Abstract

The invention discloses a rapid intestinal release detection device for coated sustained-release products, which belongs to the technical field of sustained-release products and comprises a device body, an inner cylinder at the center of the interior of the device body and a multi-way tube connected with one end of the device body. Extrusion cavities are formed in the positions, on the outer side of the inner cylinder, in the device body at equal intervals with the inner cylinder as the circle center, sampling cavities are formed between the positions, at one ends of the extrusion cavities, of the device body and the inner cylinder, the interiors of the sampling cavities are slidably connected with first pistons, first piston rods are fixed to one sides of the first pistons, and a catalyst storage cavity is fixed at the end part of the device body on the inner side of the multi-way tube. According to the invention, urine is sampled in the reciprocating process of the first piston rod and the first piston through pressing, an accelerating agent is synchronously added in the sampling process, meanwhile, the rotating disc is driven to rotate through hydraulic reciprocating motion, an arc-shaped plate is made to move repeatedly, a knocking head knocks the sampling cavity, and the reaction speed of the accelerating agent and the urine is increased.

Description

technical field [0001] The invention relates to the technical field of sustained-release products, in particular to a rapid detection device for intestinal release of coated sustained-release products. Background technique [0002] Sustained-release drugs in coated sustained-release products, also known as sustained-release preparations, refer to preparations that release drugs at a slow and non-constant rate in a prescribed release medium after oral administration. Compared with corresponding ordinary preparations, the frequency of administration is at least reduced, and Can significantly increase patient compliance or reduce drug side effects. [0003] After the coated sustained-release drug is eaten, it will be digested by the intestinal tract so that the coated sustained-release drug will be released slowly. In order to detect the release rate of the coated sustained-release drug in the human or animal intestinal tract, it is necessary to test the Sampling of urine disc...

AI Technical Summary

Problems solved by technology

[0003] After the coated sustained-release drug is eaten, it will be digested by the intestinal tract so that the coated sustained-release drug will be released slowly. In order to detect the release rate of the coated sustained-release drug in the human or animal intestinal tract, it is necessary to test the Sampling of urine discharged by animals is used to observe the absorption of sustained-release drugs by humans or animals. However, in the existing urine sampling, it is impossible to achieve simultaneous absorption of urine The absorption of catalysts or additives has a slow fusion speed, which affects the effect of the test. At the same time, it is impossible to continuously tap the absorbed urine and catalysts or additives during the urine absorption process, so that urine and catalysts or Additives vibrate, do not speed up fusion, and are inconvenient to use

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