Supercharge Your Innovation With Domain-Expert AI Agents!

Device for preparing compound paracetamol and amantadine hydrochloride pills

A technology of compound acetaminophen and mixing unit, which is applied in the fields of pill delivery, pharmaceutical formulation, sugar-coated pills, etc., and can solve problems such as the disclosure of mixing equipment and the structure of undisclosed coating and granulating machines

Pending Publication Date: 2021-08-31
浙江亚峰药厂有限公司
View PDF8 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this patent does not propose an effective solution to the problem of uniform mixing of acetaminophen, amantadine hydrochloride and artificial bezoar, nor discloses the mixing equipment to be used, nor discloses the structure of a suitable coating granulator
[0006] The inventor's in-depth and extensive research has found that the process of preparing compound acetaminophen pellets from amantadine hydrochloride, acetaminophen, chlorpheniramine maleate, artificial bezoar and caffeine is uniformly mixed and automated. There are two problems in production, and the problem of uniform mixing involves three problems of mixing equipment, process flow and process parameters to be solved

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Device for preparing compound paracetamol and amantadine hydrochloride pills
  • Device for preparing compound paracetamol and amantadine hydrochloride pills
  • Device for preparing compound paracetamol and amantadine hydrochloride pills

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] A device for preparing compound amphetamine pills provided by the present invention comprises a grade A mixing unit, a grade B mixing unit, a grade C mixing unit, a D granulation unit and a control unit.

[0074] The control unit includes a time control unit, a temperature control unit, a flow control unit, a particle size control unit and a pressure control unit connected to each mixing subunit.

[0075] The outlet of the A-level mixing unit is connected with the feed inlet and the third coating section of the D granulation unit respectively through a tee; wherein, the mixture sent into the feed inlet is the core pellet mixed with water, and the core pellets are prepared. The pellets are prior art, and the present invention is not shown; the feeding material connected with the third coating section of the D granulation unit is the coating material mixed with water.

[0076] The outlet of the B-level mixing unit is respectively connected to the inlet of the C-level mixi...

Embodiment 2

[0096] A preparation process for preparing compound acetaminophen pills. Compound acetaminophen pills are prepared from chlorpheniramine maleate, artificial bezoar, caffeine, amantadine hydrochloride, acetaminophen and dextrin in parts by weight The compound acetaminophen pills comprise a pellet core prepared in sequence, an intermediate layer sprayed twice and an outer layer sprayed.

[0097] Attached below figure 1 and Figure 4A The preparation process for the preparation of compound amphetamine pills provided by the present invention is described in detail, unless otherwise specified, the parts of each material in the present invention are in parts by mass:

[0098] (1) Preparation of core pills: respectively, paracetamol 125, amantadine hydrochloride 50, and artificial bezoar 50 Figure 1A Supported by the support frame shown, premixed by a feeding screw, a motor, and a premixing port with a rotary rotor, it is sent into the mixing unit A through the discharge port and ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a device for preparing compound paracetamol and amantadine hydrochloride pills. The device comprises an A-stage mixing unit, a B-stage mixing unit, a C-stage mixing unit, a D granulation unit and a control unit. A process comprises the following steps: preparing the compound paracetamol and amantadine hydrochloride pills from a mixed pill material of the A-stage mixing unit through a channel in a tee joint on an outlet side by a granulation mechanism, and feeding the pills into a feeding hole of the Dgranulation unit, and feeding mixed slurry of the unit into a third coating section of the D granulation unit through another channel in the tee joint. According to the technical scheme provided by the invention, the defects that each mixing unit is non-uniform in mixing, and the component distribution is non-uniform in 'spare' or 'standby' in the manufacturing process are overcome, the situation that all production steps are lack of unified and coordinated management is realized, and the production efficiency is greatly improved.

Description

technical field [0001] The invention relates to a pill manufacturing device, in particular to a device for preparing compound amphetamine pills and a preparation process thereof. Background technique [0002] The invention relates to a compound phenalkamine capsule, which belongs to a compound capsule preparation, and its main components are amantadine hydrochloride, acetaminophen, chlorpheniramine maleate, artificial bezoar and caffeine. It is used for nasal congestion, runny nose, sneezing, sore throat, headache, fever, etc. caused by colds, and can also be used for the prevention and treatment of influenza. [0003] "The Chinese invention patent application with the publication number CN1742751A discloses a compound aminophenamine dripping pill and a preparation method thereof. The method is to mix acetaminophen, amantadine hydrochloride, artificial bezoar, caffeine, Chlorpheniramine is mixed with the dripping pill base, heated to melt, stirred evenly, dripped with a coo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): B01F13/10B01J2/04A61K35/413A61K9/36A61P11/00A61P11/02A61P11/04A61P29/00A61P25/00A61P31/16A61K31/13A61K31/167A61K31/4402A61K31/522
CPCB01J2/04A61K31/13A61K31/167A61K31/4402A61K35/413A61K31/522A61K9/286A61P11/00A61P11/02A61P11/04A61P29/00A61P25/00A61P31/16B01F33/824A61K2300/00
Inventor 蒋绍俊陆康康江伟根喻淑丹陈婷蒋宇佳金钱露商铁存
Owner 浙江亚峰药厂有限公司
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com