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System and method for testing likelihood that subject suffers from liver cancer

A subject and possibility technology, applied in the field of biomedicine, can solve the problem that liver cancer prediction cannot meet clinical needs

Active Publication Date: 2021-09-24
PEKING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current single index for the prediction of liver cancer cannot meet the clinical needs, therefore, the development of a convenient, fast and easy-to-promote system is very important for the screening and monitoring of HCC

Method used

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  • System and method for testing likelihood that subject suffers from liver cancer
  • System and method for testing likelihood that subject suffers from liver cancer
  • System and method for testing likelihood that subject suffers from liver cancer

Examples

Experimental program
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Embodiment

[0052] 1. Inclusion criteria and basic information of research subjects

[0053] Diagnosis and grouping criteria of research objects

[0054] Diagnosis of CHB: According to the diagnostic criteria of "Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2015 Update), that is, hepatitis B virus surface antigen (HBsAg) and (or) hepatitis B virus DNA are positive for more than 6 months, and ALT continues or repeatedly rises, Or have liver histological lesions.

[0055] HBV-related cirrhosis: ① etiology shows clear evidence of HBV infection; ② clinical diagnosis or histological evidence of cirrhosis. Other common causes of cirrhosis, such as HCV infection, alcohol, and drugs, should be clarified or excluded through medical history or corresponding examinations. Clinically, it is divided into five stages according to the complications of liver cirrhosis. Stage 1: without varicose veins and ascites; stage 2: with varicose veins, without bleeding and ascites; stage ...

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PUM

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Abstract

The invention discloses a system and a method for testing the possibility that a subject suffers from liver cancer. The system comprises a data acquisition module for acquiring data of gender, age, abnormal prothrombin (DCP) and alpha fetoprotein (AFP) of a subject; and the data processing module is used for processing the data acquired in the data acquisition module, including respectively taking logarithmic functions for the DCP data and the AFP data, and further respectively setting weights for the gender, the age and the DCP and the AFP after taking the logarithmic functions, thereby calculating an evaluation value P (Y). According to the system and the method, the problem that prediction of the liver cancer by a single index cannot meet clinical requirements is solved. In addition, by means of the system, the sensitivity and specificity of liver cancer screening can be remarkably improved.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a system and method for testing the possibility of a subject suffering from liver cancer. Background technique [0002] Primary liver cancer (PLC) is the sixth most common malignant tumor in humans and the third leading cause of cancer-related deaths worldwide. The pathogenesis of liver cancer is still unclear. Epidemiological studies have confirmed that about 80% of liver cancers have a background of hepatitis B virus (HBV) or hepatitis C virus (HCV) infection. Other risk factors include Alcoholic liver disease, non-alcoholic fatty liver, long-term intake of food contaminated by aflatoxin, etc. Liver cirrhosis caused by various reasons is the main risk factor for HCC. Unlike Western countries such as Europe and the United States, my country mainly suffers from HBV infection. Among the patients with liver cirrhosis and liver cancer in my country, the proportions caused by HBV infect...

Claims

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Application Information

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IPC IPC(8): G16B20/00G16H50/20
CPCG16B20/00G16H50/20
Inventor 鲁凤民姚明解许强
Owner PEKING UNIV
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