Light treatment equipment for head irradiation, light treatment instrument and treatment method thereof

一种光治疗、设备的技术，应用在治疗阿尔茨海默症,光治疗设备及光治疗仪领域，能够解决引发癫痫、人体危害等问题

Inactive Publication Date: 2021-10-01
ZHEJIANG BRAINHEALTH MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effects of transcranial direct current stimulation and transcranial magnetic therapy can only reach the cerebral cortex, and some deep brain regions involved in functional networks, such as the medial prefrontal cortex, insula, and cingulate gyrus, cannot be further involved, and Repetitive transcranial magnetic stimulation has the possibility of inducing epilepsy, which will cause potential harm to the human body

Method used

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  • Light treatment equipment for head irradiation, light treatment instrument and treatment method thereof
  • Light treatment equipment for head irradiation, light treatment instrument and treatment method thereof
  • Light treatment equipment for head irradiation, light treatment instrument and treatment method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0109] Example 1: Single wavelength frequency irradiation animal experiments

[0110] 1. Experimental design and operation

[0111] Experimental animals: the experimental mice are APP / PS1 double transgenic mice (AD transgenic mice), and the control mice are homologous wild-type mice.

[0112] Reagents: β-amyloid specific antibody.

[0113] Experimental equipment: experimental equipment such as Figure 5 As shown in (a) and 5(b), mice were irradiated with a near-infrared LED light panel on the top.

[0114] Experimental method: when the mice were bred to 21 weeks, the near-infrared light therapy experiment was started on the mice. After 45 days of continuous irradiation treatment, 5 days of positioning and navigation training were carried out, and the space exploration test was carried out on the 6th day. On the 7th day, the mice were sacrificed and the brains were taken for immunofluorescence experiments to observe the number and area of ​​Aβ plaques in the mouse brains.

...

Embodiment 2

[0140] Example 2: Animal experiments with dual-wavelength frequency irradiation

[0141] 1. Experimental design and operation

[0142] Experimental animals: the experimental mice are APP / PS1 double transgenic mice (AD transgenic mice), and the control mice are homologous wild-type mice.

[0143] Reagents: β-amyloid specific antibody.

[0144] Experimental equipment: experimental equipment such as Figure 5 As shown in (a) and 5(b), mice were irradiated with a near-infrared LED light panel on the top.

[0145] Experimental method: when the mice were bred to 6.5 months, the near-infrared light therapy experiment was started on the mice. After 51 days of continuous irradiation treatment, the mice were sacrificed and the brains were taken for immunofluorescence experiments to observe the number and area of ​​Aβ plaques in the brains of the mice.

[0146] Experimental procedure: with reference to Example 1, the difference is that two experiments have been carried out in this ex...

Embodiment 3

[0155] Example 3: Clinical Trial of Alzheimer's Disease Light Therapy Apparatus

[0156] 1. Test plan

[0157] This study is a prospective, open, randomized, parallel controlled clinical study, including 9 subjects. Subjects who meet the test conditions will be randomly divided into the test group and the control group. The test group uses the test equipment and maintains the original intervention measures during the treatment period, and the control group maintains the original intervention measures. Finally, according to the comparison results between the test group and the control group, the effectiveness and safety of the Alzheimer's disease light therapy device in clinical application will be judged.

[0158] 2. Test equipment

[0159] Product name: Alzheimer's Disease Light Therapy Apparatus

[0160] Model: DD-1601

[0161] Production unit: Zhejiang Lion Hisilicon Medical Technology Co., Ltd.

[0162] The wavelength range is 700-1200nm, mainly composed of two kinds ...

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Abstract

Light treatment equipment (100) and a light treatment instrument (500) are provided. The equipment (100) includes a near-infrared irradiation module (110) for emitting near-infrared light to the head, and a control component (120) for controlling the operation of the near-infrared irradiation module (110) and coupled to the near-infrared irradiation module (110). A method of treatment using near-infrared light includes administering first, optionally second, optionally third, or more near-infrared light to a patient's head. The equipment and the method are used for treating Alzheimer's disease, improving functions of brain mitochondria and ATP level, promoting decomposition of beta-amyloid protein (Abeta), reducing deposition of Abeta, reducing damage to nerve cells, improving repair and regeneration capacity of nervous tissues, improving cognitive ability and the like. A treatment method using the light treatment equipment (100) or the light treatment instrument (500), and a computer-readable recording medium that controls emission of desired near-infrared light are also disclosed.

Description

[0001] This application is a divisional application of an invention patent application with an application date of June 16, 2020, an application number of 202080002238.1, and an invention title of "phototherapy equipment for head irradiation, phototherapy instrument and treatment method thereof". technical field [0002] The invention relates to the technical field of medical devices, in particular to phototherapy equipment and a phototherapy instrument for head irradiation. In addition, the present invention also relates to the field of disease treatment, in particular to a method for using near-infrared light to treat Alzheimer's disease. Background technique [0003] Alzheimer's disease (AD), commonly known as senile dementia, has a slow onset and worsens over time. The early symptoms are short-term memory impairment. As the disease progresses, language dysfunction, emotional instability, difficulty taking care of oneself, and abnormal behavior appear, eventually leading ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/06A61N5/067A61M21/00
CPCA61N5/0618A61N5/0622A61M21/00A61N2005/0659A61N2/006A61N2005/0642A61N2005/005A61N2005/0651A61N2005/0629A61N2/002A61N2005/0626A61N5/01A61M2021/0027A61M2021/0055A61M2021/0072A61M2209/088A61M2205/502A61M2209/082A61M2205/587A61M2205/3606A61M2205/3553A61M2205/3584A61M2205/3592A61M2205/3561G06F21/31A61M2205/276A61N2005/0647A61N2005/0652
Inventor 于晶索元震魏勋斌
Owner ZHEJIANG BRAINHEALTH MEDICAL TECH CO LTD
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