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Ostomy pouch

An ostomy bag and stoma technology, which can be used in colostomy, colostomy device, pharmaceutical formulations, etc., and can solve problems such as toxicity

Pending Publication Date: 2021-12-28
盐业医疗有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, known hydrophobic materials are not always suitable for use in ostomies because they often do not adhere well to polymer membranes and / or they can be toxic, e.g. fluorine-containing

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] Functionalized alumina (Al 2 o 3 ) particles were synthesized as follows. Alumina (Al 2 o 3 ) particles (d=13 nm, 10.0 g, 98.0 mmol, 1.0 equiv) and isostearic acid (39.1 g, 137.3 mmol, 1.4 equiv) were refluxed in toluene (250 mL) for 24 hours. Once the reaction time was up, the reaction mixture was collected and centrifuged at 5000 rpm for 1 hour. The solid was then recovered and centrifuged in isopropanol at 5,000 rpm for 1 hour. Next, the solid was centrifuged in ethanol at 5,000 rpm for 1 hour, centrifuged 3 times, and then dried at 80° C. for 6 hours.

[0091] functionalized with Al 2 o3 The particles are coated with a polymer film. functionalized Al 2 o 3 The deposition of the particles on the polymer film was achieved by spraying with a 2% by weight suspension in isopropanol at ambient temperature. Tri-spraying managed to achieve functionalized Al 2 o 3 Maximum coverage of particles on polymer film.

[0092] The WCA of the resulting polymer film was 1...

Embodiment 2

[0094] Functionalized iron oxide (Fe 3 o 4 ) particles were synthesized as follows. Iron oxide (Fe 3 o 4 ) particles (d=15-20 nm, 5.0 g, 21.6 mmol, 1.0 equiv) and isostearic acid (18.4 g, 64.7 mmol, 3.0 equiv) were refluxed in toluene (100 mL) under mechanical stirring for about 24 hours. Once the reaction time was up, the mixture was centrifuged at 5000 rpm for 1 hour. Next, the solid was recovered and dried at 80° C. for 6 hours.

[0095] with functionalized Fe 3 o 4 The particles are coated with a polymer film. Functionalized Fe 3 o 4 The deposition of the particles on the polymer film was achieved by spraying with a 2% by weight suspension in isopropanol at ambient temperature. Tri-spraying managed to achieve functionalized Fe 3 o 4 Maximum coverage of particles on polymer film.

[0096] The WCA of the resulting polymer film was 151.9° ± 2.1°.

Embodiment 3

[0098] The polymer film was heated and functionalized with Al as described in Example 1 2 o 3 Particle coating. Once the polymer film softens due to heating, the functionalized Al 2 o 3 The particles are sprayed onto the polymer film. The heating of the polymer film was performed as follows. First, physically attach the edge of the polymer film to the surface of the glass Petri dish. The purpose of this is to immobilize the polymer film to limit the extent to which it changes shape during heating. The dish was then heated until physical deformation of the polymer film was observed. Once physical deformation of the polymer film was observed, the functionalized Al 2 o 3 The particles are deposited onto the polymer film. Spray coating of functionalized Al with a 2.0 wt% suspension 2 o 3 particles. Five sprays to manage functionalized Al 2 o 3 Maximum coverage of particles on polymer film. Continue to heat the polymer film after each spray application to expedite th...

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Abstract

An ostomy pouch has a pair of opposed side walls, one of the side walls defines a stoma-receiving opening for, in use, receiving a part of a stoma into the ostomy pouch, one or both of the side walls being formed of a polymeric film at least partially coated on an internal surface thereof with hydrophobic particles, the hydrophobic particles includes: a metal oxide core; and a hydrocarbon chain having from 2 to 40 carbon atoms, wherein the hydrocarbon chain is chemically bound to the metal oxide core.

Description

technical field [0001] The present invention relates to ostomy bags, in particular ostomy bags wherein at least a portion of their inner surface is coated with hydrophobic particles resulting in a water contact angle (WCA) of about 140° or greater on the inner surface. The hydrophobic particles disclosed herein are non-toxic and adhere well to polymer films. Accordingly, the hydrophobic particles disclosed herein are particularly suitable for use in ostomies. Background technique [0002] An ostomy bag is a medical device that provides a means of collecting bodily waste from a stoma. An ostomy bag is most commonly found in colostomy, ileostomy, and urostomy procedures. An ostomy bag usually consists of a collection bag and a chassis (also called a flange or disc). There are one-piece ostomy bags, where the collection bag and chassis are provided as one piece, and two-piece ostomy bags, where the collection bag and chassis are provided separately to connect to each other. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F5/445
CPCA61F5/445A61L28/0007A61L28/0061A61L28/0034A61L2400/12A61L2400/10A61L2420/04A61F2310/00395A61F2310/00598A61F5/4405
Inventor I·波纳L·特雷韦A·巴伦D·希尔S·亚历山大
Owner 盐业医疗有限公司