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Medical application of monascus in preparation of anti-coccidiosis medicine and preparation of monascus

A Monascus, anti-coccidiosis technology, applied to medical preparations containing active ingredients, drug combinations, anti-infectives, etc., to overcome the use of chemical drugs or vaccines, high safety, weight gain and anti-infection Effect

Pending Publication Date: 2022-02-22
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its role in anti-parasites has not been reported after searching relevant literature

Method used

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  • Medical application of monascus in preparation of anti-coccidiosis medicine and preparation of monascus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] PDA medium preparation:

[0014] Take 1L of potato juice, add 10g of glucose, and adjust the pH to 6.0. Solid medium needs to add 2% agar. Sterilization conditions: 115°C, 30min.

Embodiment 2

[0016] Potato juice (PDA) medium:

[0017] Take fresh potatoes, peel them, cut them into small pieces, take 200g, add 1L of distilled water, boil on a high heat in an induction cooker, and then time it on a low heat for 1 hour. Then filter with gauze (8 layers), and make up the filtrate to 1L with distilled water, which is the required potato juice.

Embodiment 3

[0019] Inoculate and cultivate Monascus:

[0020] Streak culture of Monascus (AS3.554) on PDA medium, and then use a sterile syringe needle to take 4-5 colonies of Monascus cultured on PDA medium with a size of 1 square centimeter in 500ml of potato juice (PDA) in liquid medium. Shake at 150r / min, culture at 30°C for 7-10 days until the color turns dark red (see attached figure 1 ).

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PUM

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Abstract

The invention discloses medical application of monascus in preparation of an anti-coccidiosis medicine and a preparation of monascus, and discloses novel medical application of the monascus, fermentation liquor and mycelium, especially application in preparation of the medicine for resisting coccidiosis of animals such as chickens and the like. The fermentation liquor and mycelium of the monascus provided by the invention are non-toxic and high in safety; and the defects of chemical medicine use or vaccine use in the prior art in the industry are overcome, and the advantages of weight increment and good infection resistance are achieved.

Description

technical field [0001] The invention discloses the medical use of Monascus in the preparation of anti-coccidiosis drugs, which is a new medical use and can be used as a new type of feed or drinking water additive for resisting coccidiosis of chickens and other animals, belonging to poultry microbiota. Ecological preparation technology field. Background technique [0002] Coccidiosis is an important protozoan disease of animals. Chicken coccidiosis is an important parasitic disease that is harmful to the development of chicken industry caused by a variety of Eimeria coccidiosis parasitic in the chicken intestine. For many years, the main means of controlling chicken coccidiosis is chemical drugs. Although these drugs have played an important role in the prevention and control of chicken coccidiosis, they are still facing the threat of coccidiosis outbreaks due to the emergence of drug-resistant strains. In addition, chemical drugs inevitably cause residues in chicken and egg...

Claims

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Application Information

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IPC IPC(8): A61K36/062A61P33/02
CPCA61K36/062A61P33/02A61K2236/19
Inventor 张西臣肇英池张楠李建华宫鹏涛王晓岑李新马赫然杨举
Owner JILIN UNIV
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