Magnetic resonance fingerprint imaging method with variable echo number

An imaging method and magnetic resonance technology, applied in medical science, instrumentation, telemetry patient monitoring, etc., can solve problems affecting the quantitative accuracy, time-consuming, and acceleration of adipose tissue

Pending Publication Date: 2022-03-11
ZHEJIANG UNIV
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Problems solved by technology

[0004] Another source that will affect the quantitative accuracy of magnetic resonance fingerprints is fat. The resonance frequency of fat has a certain frequency shift compared with water, and the relaxation time of the two is also different. Therefore, the actually collected signals are water and fat. the sum of the signals; if fat is ignored, it will affect the quantification accuracy of adipose tissue
At present, the main solutions include the foll

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  • Magnetic resonance fingerprint imaging method with variable echo number
  • Magnetic resonance fingerprint imaging method with variable echo number
  • Magnetic resonance fingerprint imaging method with variable echo number

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[0030] In order to describe the present invention more specifically, the counting scheme of the present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0031] The core of the present invention is to design and realize the sequence of magnetic resonance fingerprint imaging with variable echo number. The key to variable echo number MRF is the difference in the number of echoes in each TR, such as figure 1 As shown, the duration of each TR is different, and the number of echoes is also different; therefore, in the specific implementation process, in addition to the flip angle (FAs, FlipAngles) of the radio frequency pulse in the traditional method, the repetition time TRs, and the echo time TEs In addition to optimization, parameters such as the number of echoes need to be designed and optimized.

[0032] The specific implementation of the magnetic resonance fingerprint imaging method in this embodiment mainly ...

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Abstract

The invention discloses a variable-echo-number magnetic resonance fingerprint imaging method, and the method also introduces the change of the number of echoes besides the conventional MRF coding through the conversion of an excitation pulse angle, so that quantitative diagrams of B0, B1 + and T1 can be obtained through single scanning. Furthermore, if the echo time corresponding to the same phase, the opposite phase and the same phase of the water and the fat is set for the three continuous echoes, the water and the fat can be imaged, and accurate quantification of B0, B1 + and the like is achieved. In-vivo experiments and simulation prove the effectiveness of the invention, so that the invention can provide various information representations for common brain diseases (glioma) and fat diseases (such as lipoma, fatty liver and the like), and is beneficial to clinical diagnosis and treatment.

Description

technical field [0001] The invention belongs to the technical field of magnetic resonance imaging, and in particular relates to a magnetic resonance fingerprint imaging method by changing the number of echoes. Background technique [0002] Magnetic resonance fingerprinting (Magnetic Resonance fingerprinting, MRF) is a relatively accurate MRI quantitative acquisition method. It encodes signals by introducing pseudo-random changes in sequence parameters, and can obtain multiple tissue parameters through one acquisition. Signal, and then through steps such as establishing a signal evolution dictionary and pattern matching, the quantitative parameter value of each pixel of the collected image signal can be obtained, including T 1 (longitudinal relaxation), T 2 and (Lateral relaxation), etc. These parameters are used to describe the physiological characteristics of tissues and organs, and have important significance and reference value for scientific research and clinical diag...

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Application Information

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IPC IPC(8): A61B5/00A61B5/055A61B5/1172G06V10/772
CPCA61B5/004A61B5/0042A61B5/055A61B5/1172A61B5/72
Inventor 叶慧慧徐金旻刘华锋
Owner ZHEJIANG UNIV
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