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Nano carbon tube reinforced high-molecular composition for repairing bone

A composite material, carbon nanotube technology, applied in medical science, prosthesis, etc., can solve problems such as unsuitable force-bearing bone repair, non-bacterial inflammatory response, and inability to promote bone cell growth.

Inactive Publication Date: 2004-03-17
TSINGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when this kind of polymer degrades, it will cause acid accumulation, which may cause a non-bacterial inflammatory response clinically, and has no osteoconductivity, cannot promote the growth of bone cells, and degrades quickly, so it is not suitable for the main load-bearing bone. repair

Method used

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  • Nano carbon tube reinforced high-molecular composition for repairing bone
  • Nano carbon tube reinforced high-molecular composition for repairing bone
  • Nano carbon tube reinforced high-molecular composition for repairing bone

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Fill the fully ground and mixed PHB powder (97wt%) and carbon nanotubes (3wt%) figure 1 In the cavity of the upper mold shown, and preset large-grained PHB raw materials in the cavity of the upper mold to prevent the powder from falling. at 3×10 7 It was extruded into the cavity of the lower die at 120° C. under Pascal pressure, the die was cooled to room temperature and the extruded sliver was taken out.

Embodiment 2

[0025] Fill the fully ground and mixed PHB powder (95%) and carbon nanotubes (5wt%) figure 1 In the cavity of the upper mold shown, and preset large-grained PHB raw materials in the cavity of the upper mold to prevent the powder from falling. in 8×10 7 It was extruded into the cavity of the lower die at 110° C. under Pascal pressure, the die was cooled to room temperature and the extruded sliver was taken out.

Embodiment 3

[0027] Fill the fully ground mixed PHB powder (92.85wt%), carbon nanotubes (7wt%) and nucleating agent ammonium chloride (0.15wt%) figure 1 In the cavity of the upper mold shown, and preset large-grained PHB raw materials in the cavity of the upper mold to prevent the powder from falling. at 3×10 8 It was extruded into the cavity of the lower die at 100° C. under Pascal pressure, the die was cooled to room temperature and the extruded sliver was taken out.

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Abstract

A nanometre carbon tubes reinforced high-molecular material-base composition for repairing bone is prepared from the microbially synthetic hydroxy fatty acid ester (PHA) as matrix and nanometre carbon tubes as reinforcing material. Its advantages are good biodegradability, biocompatibility and electric conductivity, unique piezoelectric performance and sufficient mechanical strength.

Description

technical field [0001] The invention relates to a composite material for bone repair, which belongs to the field of biomedical materials. Background technique [0002] At present, the commonly used bone repair materials are mostly metals and their alloys, or ceramics. Due to the large difference in stiffness between this material and the stiffness of bones, the normal stress environment in the process of bone healing is destroyed and the formation of callus is hindered. Metallic materials can also cause inflammation due to corrosion and require secondary surgery to remove. There are also reports abroad that chemically synthesized polylactic acid (PLA), polyglycolide (PGA), etc. are used as degradable bone repair materials. However, when this kind of polymer degrades, it will cause acid accumulation, which may cause non-bacterial inflammatory response clinically, and has no osteoconductivity, cannot promote the growth of bone cells, and degrades quickly, so it is not suitabl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/44
Inventor 胡平方壮熙王东瑞
Owner TSINGHUA UNIV