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Application of philippine in preparation of medicine for treating and preventing acute pneumonia

A kind of acute pneumonia, a thousand-pound technique, applied in the field of medicine, to improve the survival rate and improve the effect of lung injury

Pending Publication Date: 2022-04-08
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the drugs and methods used to treat pneumonia are different from those used in the treatment of lung cancer.

Method used

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  • Application of philippine in preparation of medicine for treating and preventing acute pneumonia
  • Application of philippine in preparation of medicine for treating and preventing acute pneumonia
  • Application of philippine in preparation of medicine for treating and preventing acute pneumonia

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Embodiment Construction

[0021] The present invention will be further described in detail below in conjunction with the accompanying drawings, so that those skilled in the art can implement it with reference to the description.

[0022] It should be noted that the experimental methods described in the following embodiments, unless otherwise specified, are conventional methods, and the reagents and materials, unless otherwise specified, can be obtained from commercial sources.

[0023] Experiment 1: Study on the effect of Qianjinbasu on acute pneumonia induced by lethal dose of lipopolysaccharide (LPS)

[0024] 1 Materials and methods

[0025] 1.1 Drugs and reagents

[0026] Qianjinbasu (laboratory extraction); LPS (SIGMA company, batch number 088M4067V); dexamethasone (Henan Runhong Pharmaceutical Co., Ltd., batch number: 190321); normal saline for injection (Sichuan Kelun Pharmaceutical Co., Ltd., batch number : L219012211).

[0027] 1.2 Experimental animals

[0028] Healthy BALB / c mice, 60 males...

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Abstract

The invention discloses application of philippine in preparation of a medicine for treating and preventing acute pneumonia. The structural formula of the philippine is as shown in formula (I). The philippine has a certain protective effect on pneumonia model mice.

Description

technical field [0001] The invention relates to the technical field of medicine. More specifically, the present invention relates to the use of a kind of jackalin in the preparation of medicines for the treatment and prevention of acute pneumonia. Background technique [0002] Community Acquired Pneumonia (CAP) refers to the inflammation of the terminal airways, alveoli and pulmonary interstitium, which is caused by pathogenic microorganisms, physical and chemical factors, immune injury, allergies and drugs outside the hospital. Mycoplasma and bacterial pneumonia are the most common pneumonias and the most common infectious diseases. In recent years, with the increase of air pollution PM2.5, the incidence of pneumonia has a tendency to increase. Some scholars have conducted statistics on the mortality rate of pneumonia, which is less than 1% to 5% for outpatients, about 12% for inpatients, and as high as 40% for those admitted to the intensive care unit. Pneumonia account...

Claims

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Application Information

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IPC IPC(8): A61K31/352A61P11/00
Inventor 高红伟苑仁祎坤奉建芳冯育林杨世林
Owner GUANGXI UNIV OF CHINESE MEDICINE
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