Water-based micro-droplet lossless operation device and preparation method

Abstract

The invention relates to a water-based micro-droplet lossless operation device and a preparation method. The operation device comprises a low-adhesiveness super-hydrophobic film and a clamp base body. The clamp base body comprises a first clamping part, a second clamping part and a holding part, the holding part is connected with the first clamping part and the second clamping part, the first clamping part and the second clamping part can be opened and closed under the control of the holding part, the surfaces, making contact with water-based micro-droplets, of the first clamping part and the second clamping part are in a groove shape, and the surfaces, making contact with the water-based micro-droplets, of the first clamping part and the second clamping part are in a groove shape. And a low-adhesiveness super-hydrophobic film is adhered to the surface. A low-adhesion super-hydrophobic structure is prepared on the surface of a thin film material, a super-hydrophobic thin film is pasted on the surface of a designed and manufactured flexible clamp, lossless operation of microliter-scale water-based liquid drops is achieved, the method is easy to operate, external field action intervention is not needed, and the limitation that micro-liquid-drop operation efficiency is low, and precise lossless operation is difficult to achieve is broken through.

Description

Technical field [0001] The present invention relates to the field of functional structural laser microbial manufacturing techniques, and more particularly to a non-destructive operating apparatus and a preparation method prepared based on superhydrophobic function surfaces. Background technique [0002] The microlicidal droplets have a small size, large specific surface area, and have important potential applications in the fields of trace measurement, biological analysis, cell culture, chemical detection, microreactors. Microfluidic analysis techniques in the test can greatly reduce the amount of reagent and reduce the test cost. The premise of achieving microfluidic applications is to achieve precision operation of droplets, including picking, transfer, release, and the like. [0003] In the current study, the difference in bionic superhydrophilic surface adhesion to achieve pickup and release of droplets is a common method, but the high adhesion of the surface of the operation...

AI Technical Summary

Problems solved by technology

[0003] In the current research, it is a common method to use the difference in adhesion of bionic superhydrophobic surfaces to realize the pickup and release of droplets, but the high adhesion of the operating surface to droplets will cause losses during the transfer process, which is difficult to achieve lossless transfer

Using the capillary action caused by the asymmetric micro-nano structure on the surface of the material to drive the droplet movement is another method for the planar operation of the droplet. This method can realize the non-destructive transfer of the droplet, but the droplet moving speed is very slow and the operation efficiency is low. And the operable droplet volume is very limited

Therefore, scholars at home and abroad have carried out a lot of research work on external field intervention to assist droplet manipulation, using external field stimuli such as magnetic field, electric field, heat, light, and mechanical vibration to drive droplet movement and increase the speed of droplet movement. Droplets contain particles responsive to external field stimuli, and external field stimuli may cause damage to biologically active substances in the manipulated droplet

[0004] Therefore, there is still a lack of a safe, effective, simple and fast method to achieve non-destructive manipulation of large-scale micro-scale droplets.

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