Double-frequency ultrasonic microneedle array device
A microneedle array, dual-frequency ultrasound technology, applied in the field of medical devices, can solve the problems of single ultrasonic vibrator structure and poor penetration effect, and achieve the effects of achieving diversity, reducing penetration force and tissue deformation, and accelerating penetration.
Pending Publication Date: 2022-06-07
CENT SOUTH UNIV
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[0004] The purpose of the embodiment of the present application is to provide a dual-frequency ultrasonic microneedle array device to solve the technical problems in the prior art that the ultrasonic vibrator structure of the ultrasonic microneedle is single and the effect of promoting penetration is not good
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[0023] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present application clearer, the present application will be described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application, but not to limit the present application.
[0024] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.
[0025] It is to be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top" , "bottom", "inside", "outside", etc. indicate t...
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Abstract
The invention relates to the technical field of medical instruments, and provides a double-frequency ultrasonic microneedle array device which comprises a microneedle module, an acoustophoresis module and a connecting module. Array microneedles are arranged at the front end of the microneedle module, a connecting pipe connected with an injector is arranged on the side face of the microneedle module, and a cavity communicated with the array microneedles is formed in the microneedle module; the acoustophoresis module comprises a first vibrator and a second vibrator, and the connecting module is connected with the microneedle module, the first vibrator and the second vibrator. The diversity of vibrator structures can be achieved through the first vibrator and the second vibrator, in this way, the vibration mode can be changed by changing the phases of the first vibrator and the second vibrator, permeation of a medicament in the transverse direction and the depth direction of the skin can be accelerated by combining the array microneedles, the piercing force and tissue deformation are reduced, and the permeation effect is guaranteed.
Description
technical field [0001] The present application belongs to the technical field of medical devices, and more particularly, relates to a dual-frequency ultrasonic microneedle array device. Background technique [0002] Transdermal drug delivery (TDD) is a way of delivering drugs or biological compounds to the human body. Compared with the traditional subcutaneous injection and oral delivery methods, this method can avoid damage to the subcutaneous tissue and reduce the toxic and side effects of the drug on the stomach and liver. However, due to the extremely ordered lipid structure of the stratum corneum, it only allows a limited number and size of molecules to enter the skin, resulting in very inefficient transdermal drug delivery. [0003] The combination of acoustophoresis and microneedle osmosis is a very potential new method to promote the penetration of transdermal drug delivery, which can provide a physical channel for the drug to enter the dermis, and also provide the ...
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Login to View More IPC IPC(8): A61M37/00
CPCA61M37/0015A61M37/0092A61M2037/0023A61M2037/0046A61M2037/0061A61M2037/003
Inventor 陈泽宇赵爽陈翔陈紫嫣吴华翼何志友
Owner CENT SOUTH UNIV