Application of lamotrigine in medicine for treating thyroid dysfunction diseases
A technology of thyroid function and lamotrigine, which is applied in the field of medicine and can solve problems such as adverse reactions, difficulty in treating abnormal thyroid function, and treating the symptoms but not the root cause
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[0022] Experimental Example 1. Therapeutic effect of lamotrigine on patients with thyroid dysfunction
[0023] 1. Experimental method
[0024] 1.1 Case inclusion criteria: A total of 966 patients with abnormal glucose metabolism (including patients with type 2 diabetes mellitus, impaired glucose tolerance and impaired fasting blood glucose) and those with abnormal hypothalamic-pituitary-thyroid axis function were treated at West China Hospital of Sichuan University. .
[0025] Criteria for dysfunction of the hypothalamic-pituitary-thyroid axis (HPT axis):
[0026] Detect the patient's HPT axis indicators: TSH, FT4, FT3, TT4, TT3. Referring to the Laboratory Department of West China Hospital, Sichuan University, the normal ranges of hormones are as follows: TSH: 0.27-4.2mU / L, TT3: 1.3-3.1nmol / L, FT3: 3.6-7.5pmol / L, TT4: 62-164nmol / L, FT4: 12-22pmol / L, ACTH: 5.0-78ng / L, COR (8:00 am): 147.3-609.3nmol / L; range above or below the reference value was defined as "abnormal". The ...
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