58 results about "Hyperthyroids" patented technology

The invention belongs to the technical field of immunodiagnosis, and discloses a thyroxine (T4) enzymatic chemiluminescence quantitative determination kit. The kit disclosed by the invention consists of a T4 standard product, an antibody pre-coated reaction plate, a horseradish peroxidase marker, diluent, cleaning mixture, and chemiluminescence substrate liquid. The kit disclosed by the invention has the advantages of quickness, handiness, sensitiveness, cheapness and high repeatability, and is an important index for diagnosis and therapeutic evaluation of hyperthyroidism and hypothyroidism. The invention has high clinic use value. The invention also provides a method to prepare the kit.

An exterior-applied ointment for treating thyroidism is prepared from glucocorticoid, thyroidism-resistant medicines, percutaneous promoter, oily matrix, water-soluble matrix, and distilled water.

The invention relates to compositions for preventing chronic renal failure (CRF) in felines with hyperthyroidism wherein the compositions comprise (1) from about 28 to about 35% protein, the protein comprising at least about 75% vegetable protein, and (2) from about 0.1 to less than about 1 mg/kg iodine and/or from about 0.1 to about 1 mg/kg selenium. The invention also relates to compositions for treating CRF in hyperthyroid felines wherein the compositions comprise (1) from about 28 to about 35% protein, the protein comprising at least about 75% vegetable protein, and (2) from about 0.1 to less than about 0.3 mg/kg iodine and/or from about 0.1 to about 1 mg/kg selenium. The invention further relates to methods for preparing and using such compositions, articles of manufacture comprising such compositions, and means for communicating information about such compositions, methods, and articles of manufacture.

The invention provides pharmaceutical compositions for improving the bone loss of hyperthyroid high-conversion type and the reduction of the biomechanical properties of the bone, and relates to an extract of a Chinese medicinal Danshen, or the formula and the production process of pharmaceutical compositions for improving the bone loss of high-conversion type and the reduction of the biomechanicalproperties of the bone caused by the hypersplenism of the thyroid, which is prepared from the following components in parts by weight: 0.1 to 0.3 g of a danshensu and 5 g of crystalline fructose, thepharmaceutical compositions are characterized by being prepared into an injection. The invention further discloses a formula and production process of the injection, a granule and a non-alcoholic beverage. The high-dose thyroxine-induced hyperthyroid high-conversion bone loss animal model proves that the pharmaceutical composition prepared from the danshensu and the fructose can influence the bone metabolism of the rat, promote the bone formation, inhibit the bone resorption, increase the bone mass, improve the bone mineral density and the bone mineral salt content, and improve the performance of the bone biomechanics, and has a good preventive effect on the damage of the bone biological biomechanical properties of the hyperthyroid osteoporosis.

The invention relates to an injection medicament for treating hyperthyroid, which comprises the following components by weight part: 2 to 5 milligrams of dexamethasone injection, 0.5 to 1 milligram of octreotide injection, and 10 to 20 milligrams of ciclosporin A. Immune preparations such as the dexamethasone injection, the octreotide injection, the ciclosporin A and the like are adopted for treating the hyperthyroid by locally injecting the thyroid, the volume of the tumid thyroid is remarkably shrunk, and the function of the thyroid basically recovers within two months, so the injection medicament has remarkable curative effect, and can remarkably improve the remission rate of hyperthyroid and reduce the rate of relapse. Serious abnormal change, hypothyroidism and parathyroid hypofunction are not caused, and laryngeal recurrent nerve injury is also not caused. Through more than 580 cases of clinical therapy in related hospitals, the volume of the tumid thyroid is remarkably shrunk after therapy, clinical symptoms disappear, allergic response and complications are not caused, the effective percentage is nearly 100 percent, and the cure rate is as high as 98 percent.

The invention discloses traditional Chinese medicine composition medicinal liquor for treating hyperthyroidism. The medicinal liquor is mainly prepared from the following raw material medicines in parts by weight: 10-20 parts of angelica sinensis, 6-10 parts of safflower, 2-4 parts of potassium iodide (added at end), 18-25 parts of rock candy (added at end), 9-16 parts of white paeony root, 10-15 parts of uncaria, 9-15 parts of concha haliotidis, 10-20 parts of eucommia ulmoides, 10-20 parts of dogwood, 8-16 parts of radices trichosanthis, 10-20 parts of dried tangerine or orange peel, 8-16 parts of Winged Laggera Herb, 9-16 parts of jews marro, 8-15 parts of rhizoma pinelliae preparata, 9-15 parts of kelp, 8-12 parts of seaweed, 8-12 parts of oyster, 10-20 parts of wolfberry, 6-12 parts of selfheal and 6-12 parts of thunberg fritillary bulb. The traditional Chinese medicine composition medicinal liquor provided by the invention has the effects of clearing heat and calming the liver, nourishing kidney and improving eyesight and tonifying middle-Jiao and Qi and is high in clinical cure rate.

The invention discloses a traditional Chinese medicine preparation for treating hyperthyreosis and a preparation process thereof. The traditional Chinese medicine preparation is prepared from the following main medicinal raw materials in parts by weight: 10-20 parts of fructus amomi, 8-15 parts of eucommia ulmoides, 6-9 parts of herba fibraureae recisae, 5-10 parts of jews marro, 10-15 parts of raspberry, 10-20 parts of fermented soybean, 5-10 parts of fried nux prinsepiae, 15-20 parts of fried spina date seed, 9-16 parts of raw semen cuscutae, 8-12 parts of rhizoma pinelliae preparata, 8-12 parts of fritillary bulb, 8-12 parts of seaweed, 5-10 parts of raw oyster, 10-20 parts of angelica, 10-20 parts of yam, 9-16 parts of pericarpium citri reticulatae, 8-12 parts of safflower, 7-15 parts of dogwood, 10-20 parts of radix trichosanthis and 15-20 parts of semen boitae. The traditional Chinese medicine preparation disclosed by the invention is safe and effective, free of adverse reactions, and capable of avoiding recurrence, effectively eliminating or relieving clinical symptoms of hyperthyroidism and conditioning integral organism function.

The invention provides a traditional Chinese medicine composition for treating hyperthyroidism and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw medicinal materials: radix aristolochiae, clam shell, dried tangerine or orange peel, sea-tangle, marine algae, cuttlebone, air potato, seed of feather cockscomb, radix bupleuri, rhizoma cyperi, radix paeoniae alba, ligusticum wallichii, pericarpium citri reticulatae viride, pinellia ternate, wild amaranth, clematis apiifoli, sargentodoxa cuneata, native copper, selfheal spike, rhizoma dioscoreae nipponicae, cretinism drug, nemacystus, valerian and nogra merr. The traditional Chinese medicine composition has the following beneficial effects: according to the traditional theory of traditional Chinese medicine in our country, the traditional Chinese medicines in the composition have functions in softening hardness to dissipate stagnation, promoting blood circulation to remove blood stasis, smoothing liver-qi stagnation, regulating qi-flowing for eliminating phlegm, by adoption of the composition, the internal secretion can be regulated, the immunity is improved, the normal function of a thyroid can be recovered, therefore the traditional Chinese medicine composition has advantages of fast acting, significant effect, high security, no side and toxic effect and less recurrence in the treatment of hyperthyroidism.

The invention belongs to the field of medicines, and relates to a traditional Chinese medicinal composition for treating hyperthyroidism, and a preparation method and application thereof. The traditional Chinese medicinal composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 10-20 parts of morinda officinalis, 12-18 parts of sculellaria barbata, 6-10 parts of semen cassiae, 10-15 parts of paniculate swallowwort root, 10-20 parts of ligusticum wallichii, 12-16 parts of wild chrysanthemum flower, 6-9 parts of salviae miltiorrhizae, 20-30 parts of momordica grosvenori, 20-30 parts of astragalus membranaceus, 10-16 parts of radix bupleuri, 12-18 parts of poria cocos, 15-25 parts of scutellaria baicalensis, 10-20 parts of tribulusterrestris, 6-12 parts of radix paeoniae alba, 15-20 parts of rhizoma atractylodis macrocephalae and 10-15 parts of liquorice. The traditional Chinese medicinal composition has the advantages of exact curative effect and low side effect when being used for treating hyperthyroidism.

The invention discloses medicinal liquor suitable for being drunk by patients with hyperthyroidism. The medicinal liquor is characterized by being prepared from the following raw material medicines in parts by weight: 9-12 parts of codonopsis pilosula, 8-14 parts of ginseng, 15-20 parts of angelica sinensis, 6-9 parts of safflower carthamus, 15-25 parts of pericarpium citri reticulatae, 9-16 parts of rhizoma pinelliae preparata, 8-12 parts of kelp, 2-4 parts of potassium iodide (added later), 10-20 parts of crystal sugar (added later), 15-20 parts of platycladi seeds, 9-16 parts of galangal, 9-16 parts of cistanche, 10-20 parts of cape jasmine, 8-12 parts of herba fibraureae recisae, 9-14 parts of ternate buttercup root, 10-16 parts of bergamot, 10-20 parts of radix polygonati officinalis, 9-15 parts of perilla stem, 8-12 parts of seaweed, 8-12 parts of raw oyster shells and 15-30 parts of wolfberry. The excellent effects of the medicinal liquor disclosed by the invention are further expressed as follows: the traditional medicine properties are organically combined with the traditional Chinese medicine modern pharmacology, the medicines are used for forming a prescription, and the curative effect is enhanced; the medicines of the medicinal liquor disclosed by the invention have the effects of soothing liver and strengthening spleen, clearing heat and relieving pain, and tonifying middle-jiao and qi, and are exact in curative effect on hyperthyroidism and free from side effects; the medicinal liquor disclosed by the invention is easily available in medicine source, low in medicinal material cost, and capable of reducing the burdens of the patients.

The invention relates to methimazole microemulsion, methimazole microemulsion-based gel and a preparation method and application of the methimazole microemulsion. The methimazole microemulsion comprises methimazole, oil, surfactant, cosurfactant, water and transdermal Enhancer according to a weight ratio of 1:(1.40-4.25):(5.13-15.45):(5.13-15.45):(1.40-8.32):(0.26:1.26). The methimazole microemulsion-based gel is prepared by adding gel matrix into the methimazole microemulsion, allowing swelling and performing uniform mixing. The methimazole microemulsion and the methimazole microemulsion-based gel are directly applicable to affected parts, are also applicable to the preparation of hyperthyroidism pharmaceuticals such as patches or plasters, and have the advantages such as good solubility, high penetration capacity, long acting time, evident improvement in therapeutic effect, fewer times of administration, and convenience of administration.

The invention belongs to the field of medicines, and discloses application of methimazole in serving as and/or preparation of a metal beta-lactamase inhibitor. The invention discloses the application of the methimazole and/or the derivative thereof in serving as and/or preparation of the metal beta-lactamase inhibitor for the first time, the methimazole and/or the derivative thereof has a good inhibition effect on metal beta-lactamase, can protect antibiotics from being degraded by bacteria, improves the sensitivity of the bacteria to the antibiotics, and reversing drug resistance of the bacteria to the antibiotics; and meanwhile, the methimazole and/or the derivative thereof have a good synergistic effect when being combined with the antibiotics, and can be used as an adjuvant drug for inhibiting the bacteria. The methimazole has small toxic and side effects on human bodies under normal clinical use dosage, and has good safety in many years when being clinically used as a medicine for treating hyperthyroidism.

The invention discloses a traditional Chinese medicine preparation for treating hyperthyroid heart diseases. Traditional Chinese doctors believe that hyperthyroid heart diseases belong to the categories of goiter and palpitation. Though the disease location of hyperthyroid heart diseases is heart, hyperthyroid heart diseases are caused by goiter and are frequently suffered by people having extreme changes of emotions; the traditional Chinese medicines including rhizome of longspurred fairybells, pedicularis muscicola, Japanese angelica tree root bark, dewberryleaf cinquefoil herb, albizia flower, marigold, catharanthus roseus, amethyst, rose and arabian jasmine flower and having the effects of tonifying qi, nourishing yin, calming nerves and soothing liver-qi stagnation are decocted with water to form decoction; found from clinical tests, the total effective rate is 95.6%; the traditional Chinese medicine preparation for treating hyperthyroid heart diseases is obvious in curative effect, low in treatment cost and simple and convenient in method and is worthy of being popularized and applied clinically.

The invention provides a new application of lamotrigine in a medicine for treating thyroid dysfunction diseases. Lamotrigine can treat thyroid dysfunction and promote thyroid function indexes to recover to a normal range; on one hand, the lamotrigine is good in safety, and even if the lamotrigine is taken for a long time, the lamotrigine does not cause adverse reaction or thyroid damage like an anti-hyperthyroidism medicine, so that the lifelong hypothyroidism is More importantly, lamotrigine can cure abnormal onychomycosis, so that a patient can be cured and the drug is stopped, and thyroxine is not required to be used for the lifetime like conventional hypothyroidism treatment. Even for patients who suffer from basic diseases (such as diabetes) and simultaneously suffer from thyroidism, the regulating and improving effects of lamotrigine on thyroidism are not obviously influenced by drugs for treating basic diseases, and the patients can take the drugs at the same time, so that the treatment effect of lamotrigine on thyroidism is greatly improved, and the treatment effect of lamotrigine on thyroidism is improved. And the effects of treating abnormal nail function and finally stopping medicine taking can be achieved.

The invention discloses a traditional Chinese medicine composition for treating hyperthyroidism and belongs to the technical field of medicine for treating hyperthyroidism. The traditional Chinese medicine composition is prepared from, by weight, 10-15 parts of semen raphani, 8-12 parts of white mustard seeds, 3-6 parts of orange peel, 6-9 parts of radix geutianae, 6-9 parts of radix curcumae, 8-12 parts of ophiopogon japonicus, 6-9 parts of seaweed, 6-9 parts of radix seu spiranthis lanceae, 8-12 parts of dandelions, 3-9 parts of wild buckwheat rhizomes, 6-9 parts of caulis trachelospermi, 8-12 parts of Chinese yam, 6-9 parts of Trifolium repens L., 8-12 parts of akebia stems, 10-15 parts of polygala tenuifolia, 3-9 parts of almonds, 8-12 parts of celastrus orbiculatus and 8-12 parts of cortex albiziae. The traditional Chinese medicine composition is prepared from various Chinese herbal medicine in a compatible mode, the medicine effects supplement one another and complement one another, the traditional Chinese medicine composition has the functions of clearing away internal heat and relieving depression, stimulating menstrual flow and dredging channels in a human body, and activating blood to remove stasis, directly reaches a focus, and is used for performing fundamental treatment on hyperthyroidism; the human body immune function of a patient can be enhanced, and the purpose of treating both the current symptoms and the root causes is achieved; the traditional Chinese medicine composition is mild in medicine property, convenient to take, mild and easy to take, free of side effects, short in treatment course and capable of taking effects fast, and hyperthyroidism will not relapse.

The invention discloses granules for treating senile hyperthyroidism and a preparation method thereof to solve the problem of treatment of senile hyperthyroidism. The preparation method is characterized by comprising the following steps: (1) decocting welsh onion stalks, adding coarse powder of elaeagnus angustifolia L gum to the decoction, heating the materials until the materials are molten, concentrating the solution, dropping the concentrate into cold water one by one while the concentrate is hot to cool the concentrate, and drying the products in the shade to prepare gum beads for later use; (2) grinding flos citri sarcodactylis, fineleaf schizonepeta herb, common jasminorange leaf and twig and fagopyrum dibotrys stem leaves into powder, and extracting the powder to obtain mixed essential oil; (3) poaching alpinia japonica, fiveleaf akebia fruit, fructus polygoni orientalis, scurrula parasitica, fossil fragments and rhizoma kaempferiae, filtering the solution, concentrating the filtrate, heating the concentrate, and adding and grinding the gum beads obtained in the step 1 to dissolve the gum beads; cooling the solution, adding the mixed essential oil obtained in the step 2, and mixing the materials uniformly to prepare an initial material; (4) drying and grinding the initial material obtained in the step 3 to obtain active granules. Clinical experiments prove that the granules have the characteristics of good curative effects and higher safety in conservatively treating senile hyperthyroidism and are worthy of being clinically applied and popularized.

The invention discloses a traditional Chinese medicinal oral preparation for treating hyperthyroidism myasthenia, and a preparation method thereof. The traditional Chinese medicinal oral preparation is prepared from, by weight, 15-25 parts of Radix Pseudostellariae, 15-25 parts of Radix Fici Simplicissimae, 10-20 parts of Polygonatum sibiricum, 10-20 parts of Radix Puerariae, 10-20 parts of Poria cocos, 8-16 parts of algae, 5-15 parts of Radix Aucklandiae, 5-15 parts of Pseudobulbus Cremastrae seu Pleiones, 5-15 parts of Cornus officinalis, 5-15 parts of Fritillaria cirrhosa, 4-12 parts of Achyranthes bidentata, 2-8 parts of Airpotato Yam Rhizome and 2-8 parts of Chinese magnoliavine. The traditional Chinese medicinal oral preparation is a capsule prepared from common traditional Chinese medicinal materials, covers the unpleasant odor of medicines, has the advantages of stable medicine effects, low cost, substantial curative effect, no side effects, portability and convenient administration, has the efficacy of invigorating spleen and nourishing kidney, supplementing qi and generating body fluid, and reducing phlegm and resolving masses, and can be used to effectively treat the hyperthyroidism myasthenia.

The invention discloses a traditional Chinese medicine composition for treating hyperthyroidism. The traditional Chinese medicine composition is composed of common selfheal spike extract and Chinese magnoliavine fruit extract and may be made into any pharmaceutically acceptable oral dosage form, including a tablet, a capsule, a granule, a pill and syrup. According to the invention, the raw materials are simple; cost is reduced compared with other compositions for treating hyperthyroidism; a specific traditional Chinese medicine extraction method is employed, so the recovery rates of effective components in the traditional Chinese medicines are increased; and the traditional Chinese medicine composition has improved treatment effect and small toxic and side effect.

The invention discloses a traditional Chinese medicine preparation, which is prepared from the following main active ingredients in parts by weight: 8-12 parts of rhizoma pinelliae preparata, 9-15 parts of caulis perillae, 9-15 parts of fructus aurantii, 6-12 parts of f the bulb of fritillary, 5-10 parts of sargassum, 5-10 parts of raw oyster shells, 10-15 parts of radix angelica esinensis, 15-30 parts of Chinese yam, 15-30 parts of pericarpium citri reticulatae, 9-16 parts of herba cistanches, 8-12 parts of fructus gardeniae, 10-15 parts of fingered citron, 12-25 parts of radix polygonati officinalis, 6-9 parts of herbaviolae, 3-6 parts of gypsum fibrosum, 5-9 parts of flos caryophylli, 9-16 parts of red flower, 10-15 parts of radix codonopsis, 8-12 parts of air potato, 6-9 parts of radix scrophulariae and 8-16 parts of spicaprunellae. The traditional Chinese medicine preparation is significant in effect on treating hyperthyroidism, and the preparation is simple, raw materials are easily available, the traditional Chinese medicine preparation is suitable for popular use, and has good application prospects.