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Oscillation magnetic separation device and method for flow type pre-sample treatment instrument

A magnetic separation device and magnetic separation technology, applied in magnetic separation, chemical instruments and methods, solid separation, etc., can solve the problems of multi-economic investment, long research and development cycle, etc., achieve simple mechanical structure, avoid interference, and improve processing level Effect

Active Publication Date: 2022-07-08
青岛瑞斯凯尔生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The embodiment of the present invention provides an oscillating magnetic separation device and method for a pre-flow cytometer sample processor, the purpose of which is to solve the problem that the existing pre-flow cytometer divides the magnetic separation and oscillation into two modules. During the sample process, the sample needs to be transferred multiple times and two independent modules also bring more economic investment and longer R&D cycle problems

Method used

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  • Oscillation magnetic separation device and method for flow type pre-sample treatment instrument
  • Oscillation magnetic separation device and method for flow type pre-sample treatment instrument
  • Oscillation magnetic separation device and method for flow type pre-sample treatment instrument

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Embodiment 1

[0050] Refer to the attached Figures 1 to 11 As shown, the present invention provides a technical solution: an oscillating magnetic separation device 300 for a pre-flow sample processing instrument, comprising an equipment main body 100, a test tube holder device 200, a magnetic separation device 300 and an oscillating device 400;

[0051] Refer to the attached Figures 1 to 2 As shown, the device main body 100 includes a base 110 and a first cylinder 120 and a second cylinder 130 which are sequentially arranged on the base 110 . cavity 121 and the second accommodating cavity 131 . The first cylindrical body 120 and the second cylindrical body 130 are detachably connected.

[0052] Further, a top cover 132 is combined with a sealing cover on the second cylinder body 130 , and a handle 132 a is fixedly connected to the top cover 132 . The purpose of the provided top cover 132 is to better achieve the effect of shielding from light; and the provided handle 132a is used to fa...

Embodiment 2

[0072] Refer to the attached Figure 12 As shown, another embodiment of the present invention provides a method for oscillating magnetic separation for a pre-flow sample processor, comprising the following steps:

[0073] S1, placing the biological sample: open the top cover 132 and put the microporous tube 221 containing the biological sample and the specifically bound magnetic particle solution into the microporous tray 220;

[0074] S2, the first oscillating mixing: the double-headed motor 422a is energized to drive the eccentric wheel 443 to rotate, and under the action of the limiting mechanism 430, the oscillating disk 410 can reciprocate and perform half-rotation motion, which can drive the first housing 210 and the The second housing 310 vibrates as a whole, so that the biological sample in the microporous tube 221 and the specifically bound magnetic particle solution can be fully mixed;

[0075] S3, the electromagnetic rod is raised: the first driving motor 3212 is e...

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Abstract

The invention provides an oscillation magnetic separation device for a flow type pre-sample treatment instrument and a method thereof, and belongs to the technical field of flow type pre-sample treatment instruments, the oscillation magnetic separation device for the flow type pre-sample treatment instrument comprises an equipment main body, a test tube bracket device, a magnetic separation device and an oscillation device, the equipment main body comprises a base as well as a first barrel and a second barrel which are sequentially arranged on the base, and a first accommodating cavity and a second accommodating cavity which are communicated with each other are respectively formed in the first barrel and the second barrel; the test tube bracket device comprises a first shell arranged in the second accommodating cavity and a microporous tray arranged in the first shell, so that the effect of fully and uniformly mixing a biological sample with various solutions is effectively ensured, and the treatment level of the biological sample is greatly improved; and the magnetic separation device and the oscillation device are combined, so that the economic cost is saved, the mechanical structure is simple, and the practical performance is improved.

Description

technical field [0001] The invention belongs to the technical field of pre-flow sample processing instruments, and in particular, relates to an oscillating magnetic separation device for a pre-flow sample processing instrument and a method thereof. Background technique [0002] With the rapid development of nanoscience and technology, nanomaterials are gradually applied to the field of life sciences, providing new technologies and means for the research and development of life sciences. Among them, the preparation and application of magnetic nanoparticles has become a research hotspot. Magnetic nanoparticles have the advantages of large specific surface area, superparamagnetic properties, and easy surface modification, and are widely used in the field of biomedicine. Among them, the separation of biological samples by magnetic nanoparticles is one of its important applications in this field. When magnetic nanoparticles separate biomolecules, they have special physical and c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B03C1/02B01F31/60B01F101/23
CPCB03C1/02
Inventor 纪存朋赵国强强茂王硕硕孙谧
Owner 青岛瑞斯凯尔生物科技有限公司
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