Dry powder inhaler devices, multi-dose dry powder drug packages, control systems, and associated methods
A dry powder inhaler, dry powder technology, applied in inhalers, drug devices, therapeutic insufflators, etc., can solve problems such as drug residues, the influence of stable powder distribution, and difficulty in reducing the amount of drugs
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[0131] In an experimental DPI embodiment, a piezoelectric excitation element for vibrating the powder during dispensing was employed, the DPI having a structure such that the polymer film vibration element had an associated capacitance C greater than 1800 pf. This capacitance value is related to the size or area (and thus shape) of the capsule or vibrating element. The transformer used to boost the input voltage of 5Vp-p has an inductance of about 23mH on its second side. A transformer is used to step up the voltage to the capsule excitation voltage of 150Vp-p. In this way, the transformer and the piezoelectric element are combined to form an amplifier, and the resonant frequency of the amplifier can be expressed as the following equation:
[0132] f=1 / (2π(LC) 1 / 2 )
[0133] Among them, L is the inductance of the transformer, and C is the capacitance of the polymer film vibration element. This results in a calculated resonant frequency of about 25 kHz for the experimental ...
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