Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Composition for preventing and treating climacteric sgndrome, osteoporosis and mastocancer

A technology of composition and substance, applied in the field of compositions for osteoporosis and breast cancer, prevention and treatment of menopausal syndrome, capable of solving the problems of low absorption rate, low absorption and reabsorption capacity, etc.

Inactive Publication Date: 2004-02-18
刘佳明
View PDF0 Cites 13 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Although both isoflavones and lactic acid bacteria have a variety of important physiological functions, the absorption and reabsorption of isoflavones depends on the intestinal flora, and the intestinal flora is affected by many factors, so its absorption and The ability to reabsorb is often very low, especially in middle-aged and elderly people who lack beneficial intestinal bacteria, and the absorption rate is even lower; and the way to increase estrogen levels by promoting estrogen reabsorption with lactic acid bacteria alone is also limited, because after menopause The secretion of estrogen in the body decreases sharply, and only by increasing reabsorption cannot meet the needs of the body
However, the complementary and synergistic effect presented by these two components in combination with reduced dosage is currently ignored. Therefore, it is very necessary to provide a composition of isoflavones and lactic acid bacteria that can exert a synergistic effect. of

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] beverage preparation

[0045] The ingredients were weighed and mixed according to the following recipe to provide the composition of the invention for the beverage.

[0046] Bean sprouts juice fermented liquid 10ml

[0047] Sucrose 10g

[0048] Vitamins and minerals q.s.

[0049] Fragrance q.s.

[0050] water q.s.

[0051] Total 100ml

[0052] The above-mentioned bean sprout juice fermentation broth was prepared by growing Streptococcus thermophilus and Lactobacillus bulgaricus at a ratio of 1:1 in sterilized soybean sprout juice medium (concentration: 20%) for about 48 hours to prepare a seed culture , then inoculate the seed culture into the sterilized soybean sprout medium (concentration is 20%), the inoculum size is 0.5-2%, cultivated at 37 ℃ for 24-48 hours, thus the desired Fermented liquid containing isoflavone aglycone and lactic acid bacteria, the number of viable lactic acid bacteria is controlled at 10 8 -10 9 / ml range.

Embodiment 2

[0054] Preparation of Oral Solution

[0055] The ingredients were weighed and mixed according to the following formula to provide the composition of the present invention as an oral solution.

[0056] Bean sprouts juice fermented liquid 10ml

[0057] Sucrose 2.0g

[0058] water q.s.

[0059] Total 20ml

[0060] The above-mentioned bean sprout juice fermented liquid was prepared by growing bifidobacteria in sterilized soybean sprout juice medium (concentration: 20%) for about 48 hours to prepare a seed culture, and then inoculating the seed culture into a sterilized In the soybean sprout juice culture medium (concentration is 20%) of bacteria, the inoculation amount is 0.5-2%, cultivated at 37 ℃ for 72 hours, thus can obtain the required fermented liquid containing isoflavone aglycone and bifidobacterium, The viable count of bifidobacteria was controlled at 10 8 -10 9 / ml range.

Embodiment 3

[0062] preparation of jelly

[0063] The ingredients were weighed and mixed according to the following recipe to provide the composition of the present invention in jelly form.

[0064] Bean sprout juice fermented liquid 1.6g

[0065] Juice 50.0g

[0066] Sucrose 50.0g

[0067] Agar 2.5g

[0068] Vitamins and minerals q.s.

[0069] Fragrance q.s.

[0070] The bean sprouts juice fermented liquid was prepared in the same manner as in Example 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A composite medicine contains soybean isoflavone and lactobacillus, which are obtained by fermenting the juice of germinated soybean by lactobacillus. It can be used for treating menopausal syndrome,osteoporosis and breast cancer with high curative effect.

Description

technical field [0001] The invention relates to a composition for preventing and treating menopausal syndrome, osteoporosis and breast cancer, in particular to a composition containing soybean isoflavones and lactic acid bacteria. Background technique [0002] After women's menopause, estrogen levels drop, and diseases related to estrogen deficiency, such as postmenopausal syndrome, will occur. The calcium balance in the body is disturbed due to the decrease of estrogen level, resulting in porous bone and decreased bone density, which is called osteoporosis. The decline of estrogen level is closely related to the imbalance of intestinal flora. Usually, 60% of the endogenous estrogen circulating in the body is secreted from the gallbladder into the intestine, and then reabsorbed into the blood through the action of intestinal bacteria. resume biological activity. When broad-spectrum antibiotics are used, the content of estrogen in the blood is lower than normal, and the abi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K35/745A61K35/747A61P15/12A61P19/10A61P35/00
Inventor 刘佳明孙晶刘洛贤
Owner 刘佳明
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com