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New process for preparing dripping pills and its special dripping device

A technology of dropping pills and a new method, which is applied in the direction of making medicines into special physical or taking form devices, dividing liquids into bead droplets and granulating, etc., to achieve the effects of improving accuracy and safety, and convenient differences in pill weights.

Inactive Publication Date: 2005-03-02
北京博智绿洲医药科技有限公司
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Problems solved by technology

However, due to the aforementioned technical difficulties, many traditional Chinese medicine prescriptions (especially multi-flavored Chinese medicine compound) are difficult to be prepared into practical drop pill preparations with many advantages in practice.

Method used

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  • New process for preparing dripping pills and its special dripping device
  • New process for preparing dripping pills and its special dripping device
  • New process for preparing dripping pills and its special dripping device

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Experimental program
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Embodiment Construction

[0029] Below in conjunction with several specific embodiment experiments, the new technology for the preparation of dropping pills involved in the present invention will be further described.

[0030] 1. Test of the preparation method of large-scale dripping pills

[0031] 1.1 Test of large-scale Liuwei Dihuang dripping pills

[0032] Select high-quality Chinese medicine raw materials as follows: Rehmannia glutinosa 120g, Cornus officinalis (made) 60g, Moutan cortex 45g, Chinese yam 60g, Poria cocos 45g, Alisma 45g, according to Liuwei Dihuang soft capsule (National Drug Administration-National Drug Standard WS3-102 (Z- 30)-97(Z)) and Liuwei Dihuang Oral Liquid (National Drug Administration-National Drug Standard WS3-B-3774-98), and then concentrated to obtain thick ointment or dry powder.

[0033] with polyethylene glycol 6000 As a base, the thick paste or dry powder obtained above is mixed with polyethylene glycol in parts by weight (g, kg). 6000 Mix and make uniform at a...

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Abstract

The present invention discloses the preparation of orally taken medicine composite preparation, and especially one new kind of dripping pill preparing process and special apparatus. The present invention aims at providing method and special apparatus for preparing large size dripping pill over 100 mg. The present invention features that specially designed volume rationing dripping head device is used to control the size of each medicine drop, so as to control the size of dripping pill conveniently in the pill weight difference within 2 %.

Description

technical field [0001] The invention relates to a method for preparing oral preparations of pharmaceutical compositions and special equipment thereof, in particular to a new technique for preparing dropping pills and special equipment thereof. Background technique [0002] Dropping pills use solid dispersion technology to heat and melt the active ingredients of the drug and the pharmaceutically acceptable carrier as the matrix (it can be molten liquid, turbid liquid or suspension) and drop it into an immiscible condensing agent In this method, the liquid drug droplets in the high temperature state are suddenly subjected to the tension generated on the surface when they are suddenly cooled to form a pill shape, and then condensed into a solid, which is an oral preparation of a pharmaceutical composition. Compared with conventional oral preparations, there are essential differences in the drop pills prepared by utilizing the above principles. [0003] Most of the traditional ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J3/06B01J2/06
Inventor 曲韵智赵志明刘瑞兰
Owner 北京博智绿洲医药科技有限公司
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