Fodder formulation of constructing nutritive fat animal model

A technology of feed formulation and animal model, applied in the direction of animal feed, animal feed, additional food elements, etc., to achieve the effect of high success rate, improved use efficiency, and easy promotion

Inactive Publication Date: 2005-10-19
INST OF LAB ANIMAL SCI CHINESE ACAD OF MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in these research articles, due to the variety of feed formulations and methods for constructing animal models, the obesity animal models constructed vary greatly in terms of body weight changes and blood biochemical indicators.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Take each raw material according to the following weight ratio:

[0024] Corn 25 Lard 10 Casein 8 Flour 9

[0025] Pork floss 5 grass powder 1 fish meal 3 bran 1

[0026] Mineral Salt Premix 1 Cholesterol 0.5 Vitamin Premix 0.03

Embodiment 2

[0028] Take each component raw material according to the following weight ratio:

[0029] Corn 45 Lard 20 Casein 16 Flour 18

[0030] Pork floss 15 grass powder 3 fish powder 7 bran 3

[0031] Mineral Salt Premix 3.5 Cholesterol 1.0 Vitamin Premix 0.05

[0032] The 5-week-old Wistar rats were fed with the feed formulated by this feed formula for 8 weeks, and the 5-week-old Wistar rats fed with common feed were used as a control group. Breeding conditions: All animals were clean-grade Wistar rats, kept in a clean-grade animal room, and both obese and normal feeds were used. 60 Co is sterilized, and the drinking water is sterile water provided by a sterilized water dispenser. Drinking water was changed once a week, adequate feed was ensured at any time, animals were weighed once a week, and each rat was reared in a single cage.

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PUM

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Abstract

The present invention discloses a fodder formulation for constructing nutritive obesity animal model, and especially fodder formulation for constructing nutritive obesity rat model. Obesity is dystrophic disease caused by the mutual action of genetic factors and environment factors and is inducement of several chronic diseases. The present inventor prepares fodder with the pre-mixed material of corn, lard, casein, flour, dried pork floss, grass powder, fish meal, bran and mineral salt, and the pre-mixed material of cholesterol and vitamins. The fodder is used in raising rat to obtain obesity model with obvious difference to the contrast in weight index and biochemical blood indexes. The animal model may be used as the platform for obesity research, medicine screening, and functional food development and identification.

Description

technical field [0001] The invention discloses a feed formula for building a nutritionally obese animal model, in particular a feed formula for building a nutritionally obese Wistar rat model. Background technique [0002] Obesity is a nutritional disorder caused by the interaction of genetic factors and environmental factors, and is the main cause of many chronic diseases. With the deepening of industrialization and urbanization in many countries in the world, people's intake of high-energy foods continues to increase, and the morbidity and mortality of obesity have also increased. Prevention and treatment of obesity has become the focus of the 21st century. top health concerns. Taking BMI as a measure, from 1976 to 1980, 47% of Americans were overweight or obese; and statistics in 1999 showed that the rate of overweight or obesity had risen to 61%. In the UK, in 1980, the incidence of obesity was 6% for adult males and 8% for adult females; in 1998, the incidence of obes...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K10/20A23K10/22A23K10/30A23K10/37A23K20/147A23K20/158A23K20/168A23K20/174A23K20/20A23K50/50
CPCY02P60/87
Inventor 苏卫张文明马晓红
Owner INST OF LAB ANIMAL SCI CHINESE ACAD OF MEDICAL SCI
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