52 results about "Blood Indices" patented technology

The invention discloses a composition capable of protecting liver. The composition comprises fullerene evenly dispersed in edible oil, and further comprises at least one of vitamin C, vitamin E, catechinic acid, alpha-lipoic acid, anthocyanin, curcumin, carotenoid, plant polyphenolses, plant polysaccharides, animal and plant terpene, plant flavonoid, SOD (Superoxide Dismutase), coenzyme Q10, glutathione, lactoferrin and metallothionein evenly dispersed in the edible oil. The composition effectively protects the liver and reduces the damage of the negative factor on the mouse liver, so that the blood index of the liver function tends to be at the normal range, the excellent effect of scavenging a free radical is achieved, the liver is cleared, and the redox state of the liver is improved.

The invention relates to the establishment of an animal model of non-alcoholic fatty liver disease, in particular to the establishment of a non-alcoholic fatty liver animal model induced by high fat accompanied by severe blood fat abnormality. SPF-grade male AopE- / - mice and C57BL / 6 mice were selected, randomly divided into model group and control group according to the species of mice, a total of 4 groups, 8 mice in each group, and all mice were adaptively fed with ordinary maintenance feed for 1 week. , the model group was given high-fat feed, and the control group was given control feed. After 10 weeks, the blood was drawn and sacrificed, and the four items of routine blood lipids and liver function were tested; Liver tissue was made into paraffin and frozen sections, and H.E. and oil red O staining were performed respectively to determine the effect and quality of the NAFLD model. The present invention uses a simple high-fat and high-calorie diet to make models, and creates a severe NAFLD model within a very short period of 10 weeks. The model's blood lipids, liver fat and other indicators have excellent stability and high repeatability, which is a high-quality NAFLD model. Establishment provides a reliable method.

The invention discloses lactobacillus plantarum with a function of relieving PFOA (Perfluorooctanoate) toxicity and the application of the lactobacillus plantarum, and belongs to the technical field of microorganism. The lactobacillus plantarum CCFM738 with the function of relieving the PFOA toxicity, disclosed by the invention, has acid resistance, has good endurance capacity and good adsorption capacity on PFOA in vitro and can be used for improving blood indexes and liver oxidation indexes of a PFOA-exposed mouse; the lactobacillus plantarum CCFM738 is applied to a medicine composition with the function of relieving the PFOA toxicity and a leavening agent and has a very wide application prospect.

The present invention discloses a fodder formulation for constructing nutritive obesity animal model, and especially fodder formulation for constructing nutritive obesity rat model. Obesity is dystrophic disease caused by the mutual action of genetic factors and environment factors and is inducement of several chronic diseases. The present inventor prepares fodder with the pre-mixed material of corn, lard, casein, flour, dried pork floss, grass powder, fish meal, bran and mineral salt, and the pre-mixed material of cholesterol and vitamins. The fodder is used in raising rat to obtain obesity model with obvious difference to the contrast in weight index and biochemical blood indexes. The animal model may be used as the platform for obesity research, medicine screening, and functional food development and identification.

The invention discloses a probiotic mixing preparation with anti-influenza capability and application thereof, and belongs to the technical fields of microorganisms and medicine. The probiotic mixingpreparation has an anti-influenza effect which is concretely shown in the aspects of (1) obviously relieving the weight loss degree of an influenza mouse; (2) obviously improving the blood index of the influenza mouse; (3) obviously relieving the respiratory tract infection inflammatory conditions of the influenza mouse; (4) obviously reducing the lung viral load quantity of the influenza mouse (obviously inhibiting the duplication and the value increase in the influenza mouse); (5) obviously enhancing the expression quantity of lung antivirus protein MxA of the influenza mouse. Therefore theprobiotic mixing preparation has huge application prospects in preparation of products for preventing and / or treating atopic dermatitis and preventing and / or treating the influenza.

The present disclosure relates to a strain of Pediococcus acidilactici of canine origin and an application thereof. The strain is classified as Pediococcus acidilactici and numbered JLAPCC-P76, deposited at China Typical Culture Collection on 28 July 2018, Wuhan University, Wuhan, China, with deposit number CCTCC M 2018500. Fresh faeces of puppies are taken as a sample, lactic acid bacteria strains with excellent characteristics are screened out, After feeding weaned puppies for 8 weeks, the intestinal morphology and structure, the bacterial flora and blood indexes are measured, Evaluate its digestion and absorption to puppy dog, intestinal microflora and antioxidant activity, At that same time, in order to evaluate the therapeutic effect of the screened lactic acid bacteria on the stresssymptom of the pet puppies, the present invention gives the stress puppies with anorexia and diarrhea aft long-distance transportation to be fed with lactic acid bacteria, and observes the recovery ofdiarrhea and the recovery of diet, so as to alleviate the common transport stress symptoms in the pet dog trading process.

The invention provides an esophageal squamous cell carcinoma risk prediction method based on clinical phenotype and logistic regression analysis. The method is used for realizing prognosis survival risk assessment of esophageal squamous cell carcinoma patients. The method comprises the following steps: firstly, screening out characteristic indexes according to clinical detection data of the esophageal squamous cell carcinoma patients, and constructing a decision tree classifier according to the characteristic indexes; secondly, dividing the esophageal squamous cell carcinoma patients into early-stage esophageal squamous cell carcinoma patients and middle-late-stage esophageal squamous cell carcinoma patients by utilizing the decision tree classifier; then, obtaining blood index informationof the esophageal squamous cell carcinoma patient one week before the operation, and screening out blood indexes with high correlation with the survival risk of the esophageal squamous cell carcinomapatient, and constructiung a logistic regression model; inputting the classified blood indexes of the esophageal squamous cell carcinoma patient into the logistic regression model to obtain a prognosis survival risk probability value of the esophageal squamous cell carcinoma patient; and judging the prognosis survival risk. According to the method, the postoperative survival state of the esophageal squamous cell carcinoma patient can be accurately judged, the risk prediction performance is improved, and the risk prediction cost is reduced.

The invention relates to a brittleness grading method for crisped grass carp based on living body detection, comprising the following steps of: (1) collecting blood samples of crisped grass carp fromdifferent embrittlement stages and blood samples and muscle samples of grass carp in the same batch, pretreating the muscles, and tasting and identifying the brittleness level; (2) detecting alkalinephosphatase activity, complement C3 content, and lymphocyte content in blood samples of blood samples, and establishing a blood index database of crisped grass carp mites; (3) Establishing a non-standardized Bayes discriminant function based on blood indicators; (4) using the Bayes discriminant function to determine the brittleness level of the muscles of the crisped grass carp to be determined. The brittleness grading method for crisped grass carp based on living body detection realizes a method for detecting the brittleness of crisped grass carp by live fish, which can reflect and evaluate the embrittlement effect of crisped grass carp with objective and high accuracy without killing fish.

The invention relates to the technical field of blood detection and discloses a method for calculating sex and age by using blood biochemical indexes. The method comprises the steps of blood biochemical index data collection, data preprocessing and model establishment, and data is preprocessed after sample collection. The blood indexes are used as a measurement object, the measurement comprehensiveness is improved; meanwhile, the blood indexes comprise metabolite of multiple omics; the individual aging condition can be reflected more comprehensively, aging levels are interpreted, the blood biochemical indexes are calculated through a DNN model, the whole process is more convenient, the blood biochemical indexes are transmitted into the DNN model, test results can be obtained, various parameters and model structures in a calculation model are verified for many times, the accuracy of a calculation result is guaranteed, meanwhile, the selected blood biochemical indexes are the most commonindexes in clinical use and physical examination institutions, the obtaining difficulty is low, the cost is low, the interpretation degree is high, and a result obtained after a sample is calculatedis more comprehensive.

The invention provides an esophageal cancer risk prediction method based on an SOM neural network and an SVM, and the method comprises the steps: firstly collecting M types of blood index informationand lifetime information of an esophageal cancer patient, and enabling the information to serve as an original data set; secondly, clustering the M blood indexes by using an SOM neural network to obtain a clustering result of the M blood indexes; performing regression verification on the clustering result by using a COX risk regression model to obtain N kinds of blood index information significantly related to the lifetime of the esophageal cancer patient; thirdly, finding a critical threshold value of the lifetime by drawing an ROC curve, and dividing the risk levels; and finally, optimizingSVM parameters by using a genetic algorithm, and selecting an RBF kernel function to establish an esophageal cancer risk prediction model. According to the method, a plurality of blood indexes remarkably related to the lifetime can be found at the same time through SOM neural network clustering and SVM model construction, and the risk level of the esophageal cancer is reasonably, conveniently andeffectively predicted.

The invention relates to a group of markers for reacting aspergillus flavus poisoning. Blood indexes are glutamic-pyruvic transaminase, glutamic oxalacetic transaminase, alkaline phosphatase, lactic dehydrogenase and cholinesterase. ALT, AST, LDH, ALP and CHE in the blood indexes are sensitive to animals poisoned by aflatoxin; a detection model is established by detecting contents of ALT, AST, LDH, ALP, CHE and the like in serum (plasma) and analyzing correlation with aspergillus flavus poisoning; the problems that the aspergillus flavus poisoning of animals cannot be found and treated early,the detection difficulty is high and the cost is high clinically at present are solved, the aspergillus flavus poisoning is found in time, treatment is conducted as soon as possible, and economic losses caused to animal husbandry are reduced.

The invention discloses health care wine capable of enhancing the immunity of old people and a preparation method of the health care wine. The health care wine is added with trace health care liquid cleaning cream, wherein the health care liquid cleaning cream is prepared from the following traditional Chinese medicines in parts by weight: 5 to 8 parts of codonopsis pilosula, 2 to 6 parts of acanthopanax, 7 to 13 parts of astragalus membranaceus, 1 to 4 parts of white atractylodes rhizome, 8 to 16 parts of liquorice, 2 to 5 parts of angelica sinensis, 13 to 17 parts of polygonum multiflorum, 3 to 4 parts of white paeony roots, 1 to 3 parts of colla corii asini, 4 to 6 parts of fructus lycii, 1 to 5 parts of ligustrum lucidum ait, 13 to 18 parts of semen cuscutae, 4 to 6 parts of dried red jujubes, 0.5 to 3.5 parts of rhizoma atractylodis, 1 to 2 parts of polygonum cuspidatum, 11 to 15 parts of radix polygonati officinalis, 3 to 6 parts of maca and 2 to 6 parts of purslane. According to the health care wine capable of enhancing the immunity of old people, Chinese herbal medicines capable of enhancing the immunity of a human body are mixed into the common wine; after being mixed with the wine and drunk by people, the Chinese herbal medicines have the functions of tonifying the kidney, nourishing the liver and adjusting the internal secretion of the human body, and can clear away in-vivo garbage, soften blood vessels and optimize the blood indexes; if old people drink a proper amount of the wine for a long time, the physical quality can be greatly improved, and the aim of prolonging the life is fulfilled.

Provided is a haemodialysis device in which the water removal rate can be rapidly and finely controlled so that the amount of blood can be suitably changed during haemodialysis, and in which there is an improvement in the control characteristics because the structure of the control means is simple and the operation is simplified. A haemodialysis device in which a time profile comprising target blood index values is preset as a target control line, and the dialysis conditions are controlled on the basis of blood index values measured or calculated at each control point over time in order to carry out haemodialysis, wherein the blood index value calculated taking account of the control delay at the control point one before a selected control point, the blood index value measured or calculated at that control point, and the target blood index value at the control point one after the selected control point are used to calculate the rate of water to be removed between the selected control point and the control point one after the selected control point, and water is removed between the two control points so that the target blood index value is reached.

The invention relates to a method for evaluating Dorking resistance, which comprises the following steps of: measuring the following indexes: lymphocyte conversion rate; the number of monoclonal antibody-labeled CD4+, CD8+ and T cells and a ratio of the CD4+ to the CD8+; IgG and IgM; an immunocyte index, namely absolute weight of thymus, spleen, and bursa of Fabricius, and the chicken body weight; a blood index, namely red blood cell, and total number of white blood cells, T cells and B cells in per milliliter of blood; and a cell factor index, namely interferon at 7 growth stages every two weeks from 0 to 12 weeks; and performing comprehensive evaluation on the six indexes, and using a comprehensive score as a basis for judging the degree of sample resistance. Compared with the prior art, the method for evaluating the Dorking resistance has the advantages of comprehensiveness and accuracy of Dorking resistance evaluation and wide application prospects.

The invention discloses an application of steroid saponin RCE-4 separated from pink reineckea herb in the preparation of medicines for preventing or treating tumors. The separated RCE-4 has weaker cytotoxicity to normal cells but has stronger cytotoxicity to human hepatoma carcinoma cells H22 and HepG2, has remarkable anti-tumor effects on both mice with H22-bearing ascitic tumor and solid-tumor, and has no obvious side-effect on routine blood indexes, blood biochemical indexes and histomorphology. In comparison with existing anti-cancer drugs used in clinic, steroid saponin RCE-4 has equivalent effects but small toxic and side effect.

The invention discloses a probiotic mixed preparation with anti-influenza ability and an application thereof, belonging to the technical field of microbes and the technical field of medicine. This probiotic mixed preparation has the effect of anti-influenza, which is specifically reflected in: (1) significantly improving the degree of weight loss of influenza mice; (2) significantly improving the blood indicators of influenza mice; (3) significantly improving the inflammation of respiratory tract infection in influenza mice (4) Significantly reduce the viral load in the lungs of influenza mice (that is, significantly inhibit the replication and proliferation of influenza virus in influenza mice); (5) significantly enhance the expression of antiviral protein MxA in the lungs of influenza mice, Therefore, the probiotic mixed preparation has great application prospects in the preparation of products for preventing and / or treating atopic dermatitis and even preventing and / or treating influenza.

The invention relates to an infrared angiographic catheter. The infrared angiographic catheter comprises an operation handle, a main pipe connected with the operation handle, a front end pipe connected with the main pipe, a blood index sensor installed on the main pipe, an infrared camera installed on the front end pipe, a plurality of steering shafts and a plurality of transmission wires penetrating through the operation handle and located in the main pipe and the front end pipe. The transmission wires are connected with the blood index sensor, the infrared camera and the steering shafts, andwhen the transmission wires connected with the steering shafts are electrified, the steering shafts can be contracted and bent to different degrees in a certain direction. The infrared angiographic catheter is provided with the blood index sensor, the infrared camera and the steering shafts so that the interior of the blood vessels can be observed and imaged without a contrast agent or X rays, various parameters of blood can be detected, and diagnosis and treatment operations are simple.

The invention discloses an I<2>C communication-based detection method of multiple blood indexes. The method includes the following steps: system starting, initial parameter setting, identification ofa system on test paper types and correction, reading of the system on corresponding measurement parameters of test paper, measurement starting and measurement ending. The method achieves an effect ofusing only one interface to complete identification and measurement on the multiple different types of electrochemical test paper under the same measurement equipment or the same measurement system, has a hematocrit correction function and an I<2>C communication function at the same time, and solves the problems of function monotonicity and inaccurate measurement results of existing electrochemical test paper identification and measurement.

The invention discloses a screening method for a piglet intestinal-function protection agent. The screening method includes the following steps that test piglets are divided into I piglets, II pigletsand III piglets, oral cavities of the I piglets and oral cavities of the II piglets are drenched with normal saline, and oral cavities of the III piglets are drenched with a to-be-screened additive;from the seventh day of testing, at the time 1 h after the oral cavities of the I piglets and the oral cavities of the II piglets are drenched with the normal saline, and the oral cavities of the IIIpiglets are drenched with the to-be-screened additive, the I piglets are subjected to normal saline intraperitoneal injection, and the II piglets and the III piglets are subjected to indometacin intraperitoneal injection; on the tenth day of testing, the I piglets, the II piglets and the III piglets are subjected to D-xylose oral cavity drenching at the same time, blood samples of the test pigletsare collected after 1 h, and blood indexes are measured; at the time 2 hours after the blood samples are collected, small intestine samples of the test piglets are taken, intestinal pathologic changes are observed, and the mRNA level of intestinal-function genes is detected. The screening method for the piglet intestinal-function protection agent has the advantages of being short in test cycle, high in pertinence, accurate in result and high in repeatability.

The invention relates to the technical field of big data control, and particularly discloses a big data controlled fish rapid embrittlement environment control method, which comprises the following steps: intelligently and effectively regulating and controlling a pond water body environment by using a big data monitoring technology, measuring a blood index of a to-be-embrittled fish and an elastic stress value of a corresponding muscular tissue, and calculating to obtain a fish embrittlement index. The embrittlement degree of the to-be-embrittled fish is quantitatively analyzed to serve as a reference index for intelligent regulation and control of the rapid embrittlement environment of the fish; the embrittlement stages in different culture processes are judged according to the embrittlement culture trend curve of the fish embrittlement indexes and the corresponding culture parameters, and the water body environment parameters of the fish are subjected to sectional trend analysis; by monitoring the environmental parameters of each water body in the culture pond in real time, more efficient and accurate intelligent control is realized to achieve rapid embrittlement environmental indexes, and an environmental reference standard is provided for efficient culture and standardized culture of commercial crispy meat fish.

The invention discloses a compound anesthetic for racoon dogs as well as a preparation method and application thereof, and belongs to the fields of preparation and application of compound anesthetics for racoon dogs. The compound anesthetic for the racoon dogs comprises the following components: dexmedetomidine, midazolam and water for injection. The invention further discloses a method for preparing the compound anesthetic for the racoon dogs, and the method comprises the following steps: (1) mixing the dexmedetomidine and the midazolam; (2) adding the water for injection and mixing evenly to obtain the compound anesthetic for the racoon dogs. Animal experiments prove that the compound anesthetic for the racoon dogs has an excellent anesthetic effect on the racoon dogs, and is quick and steady in induction and waking, and excellent and balanced in calming, pain easing and muscle relaxation effects; the compound anesthetic has a marginal effect on the circulatory system, the respiratory system, blood indexes and partial liver and kidney indexes, and can be applied to preparing the clinical anesthetics for the racoon dogs.

The invention specifically discloses application of a blood index for detecting the severity of a patient infected with coronavirus, comprising the following specific steps of: S1, detecting blood indexes of the hospitalized coronavirus-infected patients, and analyzing the change condition of the blood indexes; and S2, judging the severity of the patient infected with the coronavirus according tothe change condition of the blood indexes in the step S1. The blood indexes in the invention include at least one of platelet content, blood glucose content, total cholesterol content, high density lipoprotein content, low density lipoprotein content, prothrombin time, D-dimer content, and DIC score. Therefore, the severity of the coronavirus-infected patient can be accurately judged by detectingand analyzing the change condition of the blood indexes. The invention has the characteristics of timeliness, accuracy and high efficiency, and the problem that the treatment of the coronavirus-infected patient by using a clinical phenotype has a certain hysteresis phenomenon in the prior art is effectively solved.

The invention discloses a blood sampling supervision method, a blood management method, a blood transfusion supervision method and a blood management system, and belongs to the field of information management. By evaluating blood indexes of a target object in advance, the blood of the target object can be effectively examined, and the situation of invalid blood sampling is avoided; by determiningthe consistency between collection information and transportation information of blood transfusion specimens and the distribution data, the consistency between the blood transfusion specimens and thecorresponding information when the blood transfusion specimens are stored in a blood bank can be ensured; a corresponding blood transfusion specimen is obtained according to a blood getting request togenerate blood extraction information to facilitate determination of whether the blood sampling information corresponding to the blood transfusion specimen is consistent with the blood extraction information or not and check the information of the blood transfusion specimen, so that the accuracy of the blood transfusion specimen serving as a blood donation source is guaranteed, the situation thatthe blood transfusion specimen is taken by mistake or missed is avoided, closed-loop monitoring of the blood transfusion specimen is achieved by collecting an empty blood bag and recording the bloodtransfusion information of the empty blood bag, and the purpose of effectively supervising medical waste materials is achieved.

The invention discloses an oyster lipid-lowering capsule and a preparation method. In the prior art, a plurality of medicines can reduce total cholesterol, triglyceride and low density lipoprotein cholesterol, but have adverse effects. Marine organism oyster meat is reasonably matched with Chinese rhubarb, American ginseng and dwarf lilyturf roots to prepare a medicine capable of reducing the total cholesterol, the triglyceride and the low density lipoprotein cholesterol in human blood, so that the adverse effects harmful to human bodies are avoided while blood index level is reduced. Pharmacodynamic test results indicate that rise of the content of the total cholesterol, the triglyceride and the low density lipoprotein cholesterol of quails can be inhibited, the oyster lipid-lowering capsule has similar lipid-lowering functions of evening primrose oil, and the triglyceride reducing function of the oyster lipid-lowering capsule has obvious advantages, so that the oyster lipid-lowering capsule has excellent blood lipid regulating functions.

The invention relates to a brittleness grading method for crisped grass carp based on living body detection, comprising the following steps of: (1) collecting blood samples of crisped grass carp fromdifferent embrittlement stages and blood samples and muscle samples of grass carp in the same batch, pretreating the muscles, and tasting and identifying the brittleness level; (2) detecting alkalinephosphatase activity, complement C3 content, and lymphocyte content in blood samples of blood samples, and establishing a blood index database of crisped grass carp mites; (3) Establishing a non-standardized Bayes discriminant function based on blood indicators; (4) using the Bayes discriminant function to determine the brittleness level of the muscles of the crisped grass carp to be determined. The brittleness grading method for crisped grass carp based on living body detection realizes a method for detecting the brittleness of crisped grass carp by live fish, which can reflect and evaluate the embrittlement effect of crisped grass carp with objective and high accuracy without killing fish.

The invention provides a blood index detection system based on I2C (Inter-Integrated Circuit) communications. The system comprises a power supply, a test strip connector, an upper computer and an alarm module, wherein the power supply is respectively connected with the test strip connector, the upper computer and the alarm module; an output terminal of the test strip connector is connected with aninput terminal of the upper computer; and an output terminal of the upper computer is connected with the alarm module. By adopting the system, the problem that multiple detection devices need to be utilized when a conventional portable electrochemical detection instrument is used for performing detection of multiple indexes is solved; the detection of multiple blood indexes can be completed by use of one test strip detection device in the system; meanwhile the problem that the electric quantity generated by a redox reaction is easily affected by hematokrit in blood during detection is solved;the accuracy of the detection result is improved; and the system is perfect as a whole and high in reliability.

The invention discloses a method for improving milk production performance and blood indexes of dairy cows and improving milk quality, and belongs to the technical field of dairy cow breeding. According to the method, a novel cowshed illumination system is mounted in the dairy cow breeding process, and the photoperiod is controlled to be 16h+ / -5% in illumination and 8h+ / -5% in darkness. The methodis simple and reasonable, the level of melatonin in dairy cow milk can be remarkably increased, the milk production quantity of dairy cows can be remarkably increased, the capacities of triglyceride,superoxide dismutase and total oxidation resistance in dairy cow serum are improved, and the level of malondialdehyde in the serum is reduced; and in addition, the method can also reduce the somaticcell number of dairy cow milk.

The invention relates to a new use of Dendrobium officinale, and aims to provide the application of Dendrobium officinale in preparing a medicine for treating iron deficiency anemia in women of childbearing age. The invention discloses the application of Dendrobium officinale in preparing a medicine for treating iron-deficiency anemia in women of childbearing age, and a preparation method for preparing a medicine for treating iron-deficiency anemia in women of childbearing age based on Dendrobium officinale. The results showed that Tiepi Fengdou granules based on Dendrobium officinale combined with American ginseng could significantly improve the blood indexes and clinical symptoms of iron-deficiency anemia in women of childbearing age.

The invention belongs to a component determination method, and particularly relates to an external application medicine determination method based on big data blood index. The method includes: 1) bigdata analysis: 1.1, input of blood big data: inputting blood big data from exterior, comprising actual measured data and standard value data; 1.2, data normalization: performing normalization on the actual measured data and standard value data; 1.3, data unification: distinguishing the data within healthy range and the data out of the healthy range; 1.4, curve fitting; 1.5, calculation of inter-parameters: calculating the inter-parameters by three groups; 2) selection and formulation of the external application medicine: according to the calculation result, performing medicine selection and matching. The determination method has following advantages: from the blood big data, the components in the blood are analyzed, thus analyzing the reason of subhealth of people, and by which the components and ratio of the external application medicine are determined, thus guaranteeing the pertinence of the manufacturing process of the external application medicine.