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Diphase capsule of red sage root for coronary heart disease and preparation method

A Guanxin Danshen and biphasic technology is applied in the field of traditional Chinese medicine Guanxin Danshen biphasic capsule and its preparation, which can solve problems such as loss of volatile components, and achieve the effects of good stability, good stability and dilation of coronary blood vessels.

Inactive Publication Date: 2005-11-16
JIANGXI HERBFINE HI TECH
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AI Technical Summary

Problems solved by technology

Granules share the disadvantage of loss of volatile components in the drying process of tablets and capsules

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] The preparation method of Guanxin Danshen biphasic capsule is characterized in that:

[0059] (1) Preparation of volatile oil components: take the medicinal material of balsamic balsamic and pulverize, extract at 25°C, extraction pressure 35Mpa, extraction time 4h, extraction flow rate 50kg / h; collect 1.75ml of balsamic balsamic volatile oil components by CO2 supercritical extraction;

[0060] (2) Preparation of water-soluble components and alcohol-soluble components of solid dosage forms: 200 g of Danshen medicinal materials are pulverized into medium powder, add 6 times the amount of 90% ethanol for percolation, sink in water, and the supernatant is concentrated and dried as usual to obtain fine powder; Add 10 times the amount of water to the residue, extract twice, 1.5 hours each time, filter, combine the filtrates, concentrate to a thick paste, purify with D-101 macroporous resin, collect 30% ethanol eluate, concentrate, concentrate and dry as usual , to obtain fine...

Embodiment 2

[0064] Raw materials and consumption are the same as example 1. Panax notoginseng is crushed into fine powder; Danshen is crushed into medium powder, and 90% ethanol is used as solvent for percolation, the filtrate is collected, ethanol is recovered and concentrated into a thick paste; dregs are decocted twice with 10 times the amount of water, each time 1.5 hours, combined decoction, filtered, and the filtrate was concentrated to an appropriate amount, added the above-mentioned fine powder and thick paste, stirred well, made into granules, and dried; the rest of the operations were the same as in Example 1.

Embodiment 3

[0066] Raw materials and consumption are the same as example 1. Salvia miltiorrhiza and Panax notoginseng were extracted according to Example 1, and the concentrated thick paste was mixed, purified with AB-8 macroporous resin, collected 50% ethanol eluate, concentrated, concentrated and dried according to conventional methods, and obtained a fine powder. The rest of the operations are the same as Example 1.

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Abstract

A Chinese medicine in the form of dual-phase capsule for treating coronary heart disease is prepared from red sage root, notoginseng and dalbergia wood through extracting the volatile oil from dalbergi a wood, preparing its dripping pills, extracting the water-soluble and alcohol-soluble components from red sage root and notoginseng, preparing their particles and loading said dripping pills and particles is capsules.

Description

technical field [0001] The invention relates to an orally administered traditional Chinese medicine Guanxin Danshen biphasic capsule and a preparation method thereof. Background technique [0002] At present, cardiovascular and cerebrovascular diseases are common and frequently-occurring diseases that middle-aged and elderly people are prone to suffer from. They are one of the three major diseases that threaten human health. And along with the improvement of people's living standard and the change of diet structure and the prolongation of life expectancy, the incidence rate of this disease shows the obvious upward trend. Strengthening the research on the prevention and treatment of coronary heart disease and angina pectoris is an important link to reduce the pain of patients and reduce the incidence and mortality of myocardial infarction. It has also become one of the important topics in the field of medicine in the world today. Many drugs for the treatment of cardiovascula...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 杨世林吕爱平王跃生陈永洪张小娟晏永新罗晓健饶毅王少军钟铁
Owner JIANGXI HERBFINE HI TECH
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