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Catechin microcapsules production

A preparation process, catechin technology, applied in the direction of medical preparations containing active ingredients, organic active ingredients, pharmaceutical formulations, etc., can solve the problem of reducing the bioavailability of catechins, prone to oxidative polymerization or condensation, and loss of antioxidant properties Activity and other biological functions, etc., to achieve good fluidity, good stability, and high bioavailability

Inactive Publication Date: 2005-12-28
HUNAN AGRICULTURAL UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because the phenolic hydroxyl group in the catechin molecule is very active, it is very easy to oxidize, polymerize or condense under various external conditions, thereby losing its antioxidant activity and other biological functions. At the same time, it also reduces the bioavailability of catechins in the body

Method used

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  • Catechin microcapsules production
  • Catechin microcapsules production
  • Catechin microcapsules production

Examples

Experimental program
Comparison scheme
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Embodiment Construction

[0015] specific implementation plan

[0016] Take 80% ethyl cellulose and 20% polyethylene glycol by mass percentage, mix and dissolve them with edible alcohol to form an emulsion; disperse the catechin dissolved in edible alcohol in the emulsion, and make the core material : wall material=6: 4; Add edible alcohol again, make its solid substance mass ratio total content be 25%; After homogenizing with high-speed dispersing homogenizer, make whole suspension remain uniform state by high-speed stirring again; The suspension was introduced into a commercially available LPG-5 high-speed centrifugal spray dryer for spray drying to obtain catechin microcapsule products; the spray conditions were: the inlet air temperature was 130°C, the outlet air temperature was 95°C, and the feed rate was 10rpm .

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Abstract

A process for preparing the catechin microsoftgels includes such steps as proportionally mixing ethylcellulose with polyethanediol, dissolving the mixture in edible alcohol to obtain emulsion, dispersing the alcohol solution of catechin in said emulsion, adding edible alcohol, homogenizing, high-speed stirring, and spray drying.

Description

technical field [0001] The invention relates to a preparation process of a microcapsule with catechin as a core material. Background technique [0002] As a natural antioxidant and free radical scavenger, catechin has been widely used in many fields such as food, medicine and chemical industry. However, because the phenolic hydroxyl group in the catechin molecule is very active, it is very easy to oxidize, polymerize or condense under various external conditions, thereby losing its antioxidant activity and other biological functions. At the same time, it also reduces the bioavailability of catechins in the body. Contents of the invention [0003] The main problem to be solved by the present invention is to propose a process for preparing catechin microcapsules in view of the defects in the prior art. The catechin microcapsules prepared by this method have good fluidity, and the catechin microcapsules Good stability and high bioavailability in vivo. [0004] The technica...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/353
Inventor 卢向阳田云何小解罗泽民
Owner HUNAN AGRICULTURAL UNIV