Xianling gubao dripping pills having functions of reinforcing kidney strengthening bone, and its prepn method

A technology of Baodi Pills and Linggu, which is applied in the field of Xianlinggubao Diwan and its preparation, which has the function of nourishing the kidney and strengthening bones, and can solve the problem of first-pass dust utilization in the liver and intestines, which is not conducive to improving the ability of patients to seek medical treatment, and is not conducive to the overall Health level and other issues, to achieve the effect of improving bioavailability, medication safety, and high degree of automation

Active Publication Date: 2006-01-25
JIANGXI JIMINKEXIN PHARMA
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  • Abstract
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicines, have long dissolution time, low dissolution rate, poor absorption, hepatic first-pass effect and low availability of dust after taking. problems, thus affecting the efficacy of the drug, and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0030] Now with several groups of specific examples, the preparation method of Xianling Gubao dripping pills of the present invention will be further described.

[0031] [Group 1: Trials with a single substrate]

[0032] 1. Raw materials: According to [Preparation Method 1], the dry extract powder containing active pharmaceutical ingredients of 6 traditional Chinese medicine active ingredient extracts including Epimedium, Dipsacus, Salvia, Anemarrhena, Psoralen, and Rehmannia glutinosa was prepared for use;

[0033] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 60000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0034] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0035] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Xian...

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Abstract

A Chinese medicine in the form of dropping pills for nourishing kidney and treating osteoporosis, etc is prepared from 6 Chinese-medicinal materials including epimedium, dipsacus root, red sage root, rehmannia root, etc, and the pharmacologicathy acceptable carrier. It features quickly taking its high effect.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has the effect of invigorating the kidney and strengthening bones, and is used for the treatment of diseases such as osteoporosis caused by liver and kidney deficiency, blood stasis blocking collaterals, etc. An oral preparation of a pharmaceutical composition prepared from active ingredient extracts of 6 traditional Chinese medicines, such as psoraleae, rehmannia glutinosa, etc., as raw materials. Background technique [0002] Xianling Gubao Tablets prepared according to the preparation method in the national drug standard WS-10289 (ZD-0289)-2002 is a kind of medicine that has the function of nourishing the kidney and strengthening the bones, and is used for diseases caused by liver and kidney deficiency and blood stasis blocking the collaterals. Oral tablets for the treatment of osteoporosis and other diseases have been clinically verified and have definite curative effects. They ar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/296A61K36/00A61K36/53A61K36/8964A61K36/487A61K36/804A61K9/20A61P19/10
Inventor 曲韵智
Owner JIANGXI JIMINKEXIN PHARMA
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