Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Enol form lactide open-ring polymerization catalyst and its preparing method and use

A technology of ring-opening polymerization and lactide, applied in the field of enol lactide ring-opening polymerization catalyst and its preparation

Active Publication Date: 2006-08-09
ZHEJIANG HISUN BIOMATERIALS
View PDF0 Cites 42 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The biggest disadvantage of these traditional catalysts is that there is no selectivity for different configurations of lactide. When they are used to polymerize racemic lactide and meso lactide, only non-crystalline polymers can be obtained.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Enol form lactide open-ring polymerization catalyst and its preparing method and use
  • Enol form lactide open-ring polymerization catalyst and its preparing method and use
  • Enol form lactide open-ring polymerization catalyst and its preparing method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment 1: structural formula is the synthesis of the 1a catalyst of I

[0047] Under the protection condition of inert gas, the concentration is 1mol / L 4ml the toluene solution of the Schiff base of structural formula 1, and the concentration is 1mol / L 4ml AlEt 3The toluene solutions were mixed, put in an oil bath at 90° C. and stirred, reacted for 10 hours, then cooled to room temperature, and evacuated to remove volatile substances. The vacuum degree was 0.1 MPa to obtain the 1a catalyst with product structural formula I. Elemental analysis results, calculated value: C, 60.41; H, 8.33; N, 10.06; measured value: C, 61.05; H, 8.67; N, 10.51.

Embodiment 2

[0048] Embodiment 2: structural formula is the synthesis of the 1e catalyst of 1b of I, 1c of I, 1d of I or I

[0049] The enol type lactide ring-opening polymerization catalyst (557mg, 2mmol) of 1a that the structural formula that embodiment 1 obtains is dissolved in toluene, and to the toluene solution that obtains, add the methyl alcohol with the solute of this kind of toluene solution etc. , the structural formula of the present invention can be obtained as the 1b catalyst of I.

[0050] If the methanol in this embodiment is replaced by ethanol, isopropanol or benzyl alcohol respectively, and other conditions are the same, the 1c of catalyst I, the 1d of I or the 1e of I can be obtained respectively.

[0051] 1b elemental analysis results of I, calculated value: C, 55.70; H, 7.55; N, 9.99; found value: C, 55.93; H, 7.28; N, 10.20.

[0052] The elemental analysis results of 1c of I, calculated value: C, 57.13; H, 7.88; N, 9.52; found value: C, 57.35; H, 7.62; N, 9.81.

[...

Embodiment 3

[0055] Embodiment 3: structural formula is the synthesis of 2a catalyst of II

[0056] Replace Schiff base 1 in Example 1 with Schiff base 2, and other conditions are the same as in Example 1 to obtain 2a of product II. Elemental analysis results, calculated value: C, 61.62; H, 8.62; N, 9.58; measured value: C, 60.82; H, 8.40; N, 10.06.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Melting pointaaaaaaaaaa
Melting pointaaaaaaaaaa
Melting pointaaaaaaaaaa
Login to View More

Abstract

This invention relates to an enol form lactide open loop polymerized catalyst and its preparation method and also a method for polymerizing lactide by the catalyst including levo-lactied, right handed lactide, meso-lactide, dl-lactide and a mixer of any proportions between levo-lactide and right handed lactide, in which, the catalyst refers to the product reacted by an enol form Schiff base and Alethyl and their derivation.

Description

technical field [0001] The invention relates to a catalyst for ring-opening polymerization of enol type lactide, a preparation method thereof, and a method for stereoselectively polymerizing lactide using the catalyst. Background technique [0002] Polylactic acid is a very important biodegradable polymer material with good biocompatibility. It not only has the characteristics of traditional general-purpose plastics, but also does not pollute the environment after being used and discarded, and it is also widely used in the medical field, so it has developed rapidly in recent years. [0003] There are three stereoisomers of lactide: L-lactide, D-lactide, and meso-lactide. Their structures are as follows: [0004] [0005] D-lactide L-lactide Meso-lactide [0006] Polylactic acid is generally obtained by ring-opening polymerization of lactide, and there have been a large number of patents and scientific documents disclosing the preparation of polylactic acid by ring-open...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08G63/08C08G63/84
Inventor 陈学思庞烜庄秀丽杜鸿志王献红景遐斌
Owner ZHEJIANG HISUN BIOMATERIALS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com