Application of fusion protein of VEGF receptor for treating disease of eye
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- CHENGDU KANGHONG BIOTECH
- Publication Date
- 2007-02-21
Smart Images
Figure 1 
Figure 2 
Figure 3
Abstract
Description
Technical field:
[0001] The invention relates to the application of VEGF receptor fusion protein in treating various eye diseases caused by the growth of new blood vessels. Background technique:
[0002] The retinal vasculature and the choroidal vasculature are important components of the retina. Abnormal changes in the structure or function of blood vessel walls caused by trauma or disease are the main causes of vision loss or loss. For example, diabetic retinopathy (diabetic retinopathy) is the proliferation of retinal blood vessels due to diabetes, which in turn causes retinal detachment. It is the leading cause of vision loss. Growth of new blood vessels in the retina may also occur during recovery from eye injury or surgery. This type of retinal vascular proliferation is also an important cause of vision loss or blindness (Nature 438:932-938, 2005).
[0003] Age-related macular degeneration (AMD) is a disease caused by degeneration of cells or tissues and proliferat...