Composition for regulating the trophism of hair follicles and the cutaneous production of sebum and use thereof in androgenetic alopecia

A nutrient effect and composition technology, which is applied in the field of compositions for regulating hair follicle nutrient effect and skin sebum production, and can solve the problems of large variation in individual responses and the like

Inactive Publication Date: 2007-04-04
GIULIANI SPA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] However, individual responses to these types of treatments are highly variable and not always satisfactory

Method used

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  • Composition for regulating the trophism of hair follicles and the cutaneous production of sebum and use thereof in androgenetic alopecia
  • Composition for regulating the trophism of hair follicles and the cutaneous production of sebum and use thereof in androgenetic alopecia
  • Composition for regulating the trophism of hair follicles and the cutaneous production of sebum and use thereof in androgenetic alopecia

Examples

Experimental program
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Effect test

preparation example Construction

[0041] The preparation of acetone extract comprises the following steps:

[0042] - crushing the aerial part of ramie with a solvent, the weight ratio of the solvent to the medicine to be extracted is 1:10 and 1:30;

[0043] - separating the solid from the liquid and washing the residue with an additional amount of solvent;

[0044] - Concentrated and evaporated until the extract is dry.

[0045] The preparation of hydroalcoholic extract comprises the following steps:

[0046] - crushing the leaves and aerial parts of Ramie subtilis;

[0047] - Determining the water content and adding ethanol so that the drug / solvent weight ratio is equal to approximately 1:10;

[0048] - extraction, repeating two or three times until the substance to be extracted is completely extracted;

[0049] - filter and concentrate the extract by evaporating the solvent;

[0050] - May dry extract.

[0051]According to another embodiment, a hydroalcoholic extract of Ramie pilosula is used as an in...

Embodiment 1

[0094] body use

[0095] Composition of antioxidants based on ramie and isoprenoid derivatives (carotenoids, tocopherols, tocotrienols, saponins):

[0096] Consolidation in the form of tablets suitable for reducing damage to the structure of keratin due to oxidative stress caused by sun rays:

[0097] Each tablet contains:

[0098] Spermidine Trihydrochloride 0.50mg

[0099] Calcium Pantothenate 9mg

[0100] d-Biotin 0.150mg

[0101] Ramie Extract 100mg

[0102] Muscarina 5mg

[0103] Beta Carotene 7.2mg

[0104] Ubidecarenone 10.0mg

[0105] Zinc Amino Acid Chelate 7.5mg

[0106] Copper Amino Acid Chelate 1.20mg

[0107] Folic acid 0.30mg

[0108] Microcrystalline Cellulose 17.0mg

[0109] Calcium hydrogen phosphate dihydrate 62.0mg

[0110] Hydroxypropyl methylcellulose 80.0mg

[0111] Magnesium Stearate 7.90mg

[0112] Silicon dioxide 1.70mg

Embodiment 2

[0114] Food supplements based on ramie and sulfur donor compounds (sulfurized amino acids, methylsulfonylmethane) in tablet form suitable for reducing food intake deficiency:

[0115] Each tablet contains:

[0116]Methionine 300mg

[0117] Spermidine Trihydrochloride 0.50mg

[0118] Calcium Pantothenate 9mg

[0119] d-Biotin 0.150mg

[0120] Ramie Extract 200mg

[0121] Muscarina 5mg

[0122] Zinc Amino Acid Chelate 7.5mg

[0123] Copper Amino Acid Chelate 1.20mg

[0124] Manganese Amino Acid Chelate 2.25mg

[0125] Vitamin B6 3.0mg

[0126] Folic acid 0.30mg

[0127] Microcrystalline Cellulose 17.0mg

[0128] Calcium hydrogen phosphate dihydrate 62.0mg

[0129] Hydroxypropyl methylcellulose 80.0mg

[0130] Magnesium Stearate 7.90mg

[0131] Silicon dioxide 1.70mg

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Abstract

The present invention relates to a composition for regulating the trophism of hair follicles and the cutaneous production of sebum and its use in androgenetic alopecia, comprising the synergic association of an extract from Boehmeria Nippononivea with a compound active at the keratin epithelial structure level, selected from specific sulfur-donor compounds and antioxidants. The composition of the invention is suitable for topical and/or oral administration.

Description

technical field [0001] The present invention relates to a composition for regulating hair follicle trophic action and skin sebum production and its use in androgenetic alopecia. [0002] In particular, the present invention relates to food supplements and compositions for topical use, based on extracts from selected plants, in combination with other antioxidant active ingredients, with a modulating effect on the production of skin sebum and the nutritional action of keratin structures such as hair . Background technique [0003] Cosmetic problems involving seborrheic skin, where excess sebum production also causes or accelerates hair loss, is of increasing relevance in modern society. [0004] A high percentage of young people have cosmetic problems caused by seborrheic dermatitis, acne, facial furuncles, excessively oily hair with thinning hair. Considerable concern among the younger generation and others regarding these aesthetic concerns has led to an increased demand f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/00A23L1/30A61K31/00
Inventor G·朱利亚尼A·贝内杜奇S·贝林维亚F·瑞纳尔蒂
Owner GIULIANI SPA
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