Pad base for transdermal administration and needle

Abstract

The object of the present invention is to provide a pad base for endermism which hardly causes bad influence on organism even if a needle fractures in the skin and remains in the MicroPatch method. It is the pad base for endermism in which a minute needle 1 is installed upright on the skin side of a patch base 2 for skin. The minute needle 1 is formed from a biodegradable resin and is composed so as to be able to be injected an administering drug in a hollow center of an axle portion (a hollow portion 3). Even if the injection needle fractures and remains in the skin, the minute needle 1 is decomposed in vivo because it is made of a biodegradable resin; therefore, there is little bad influence is to organism.

Description

TECHNICAL FIELD [0001] The present invention relates to a pad base for endermism used when percutaneously administrating a drug which acts on organism in vivo and an injection needle. The pad base is a portion assuming the percutaneous administration of a drug in a pad for percutaneous medication. The pad for percutaneous medication is an article covering the pad base with, for example, a pressure-sensitive adhesive sheet from the reverse of the skin side, and the like. When the pad base for endermism is used, the pad base side is pasted on the skin. BACKGROUND ART [0002] The skin functions as a barrier for protecting the body and inhibits the invasion of a foreign substance in organism. Specifically, the stratum corneum of the outermost layer which is directly brought in contact with the foreign substance assumes the great role as a barrier. To be sure, although the digestive tract is the same as the skin from the viewpoint of being directly brought in contact with the foreign subs...

AI Technical Summary

Benefits of technology

[0020] Further, according to the pad base for endermism using the pad base of the present invention, as described above, percutaneous absorption can be carried out only by pasting the pad on the skin, not depending on a medication procedure by vibration. Consequently, a power source for vibration and the like is unnecessary and it is more convenient.

[0024] The minute needle of the present invention as described above may remain in the skin by positively folding this after being stung in the skin. When the minute needle is buried in the skin, the main body of the pad base for endermism is not peeled and medication is not interrupted; therefore a drug can be sustainably released for a long period of time.

Problems solved by technology

The reason why a thick needle is used in a conventional MicroPatch method as described above is that if a long thin minute needle is used, it may fracture easily and remain in the skin, and there is a there is a fear that bad influence to organism.

A thin needle is desired for mitigating pain in a usual injection needle, but when it is too thin, there is a fear of fracturing, and if it fractures, there is a fear that it remains in the skin and badly influences an organism.

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