Method of making a biosensor

Abstract

A method of making a biosensor is provided. The biosensor includes an electrically conductive material on a base and electrode patterns formed on the base, the patterns having different feature sizes. The conductive material is partially removed from the base using broad field laser ablation so that less than 90% of the conductive material remains on the base and that the electrode pattern has an edge extending between two points. A standard deviation of the edge from a line extending between two points is less than about 6 μm

Description

CROSS-REFERENCE TO RELATED APPLICATIONS [0001] The present application is a Divisional of U.S. application Ser. No. 10 / 601,144 filed Jun. 20, 2003, which is a Continuation-in-Part of U.S. Pat. No. 6,662,439, issued Dec. 16, 2003; a Continuation-in-Part of U.S. Pat. No. 6,645,359, issued Nov. 11, 2003; a Continuation in Part of U.S. Pat. No. 6,767,440 B1, issued Jul. 27, 2004; and a Continuation in Part of U.S. application Ser. No. 10 / 264,891, filed Oct. 4, 2002, each of which are hereby incorporated by reference in its entirety.TECHNICAL FIELD [0002] The present invention relates to a method of making a biosensor, more specifically a biosensor having electrode sets formed by laser ablation. BACKGROUND AND SUMMARY OF THE INVENTION [0003] Electrochemical biosensors are well known and have been used to determine the concentration of various analytes from biological samples, particularly from blood. Examples of such electrochemical biosensors are described in U.S. Pat. Nos. 5,413,690; 5...

AI Technical Summary

Benefits of technology

The present invention provides methods for making electrodes for biosensors using laser ablation techniques. These techniques allow for the formation of precise electrode edges and feature sizes, and can be performed in a high speed / throughput fashion without the use of rastering. The methods involve using a laser system and a mask to ablate through a portion of a metallic layer on an insulating base to create an electrode pattern. The resulting electrodes can be used in biosensors to analyze biological samples. The invention also provides new methods for forming electrodes using screen-printing and laser scribing techniques. Overall, the invention provides improved methods for making electrodes for biosensors.

Problems solved by technology

It is therefore appreciated that such a technique can be rather time consuming if a complex electrode pattern is to be formed on the surface.

Still further, it is appreciated that the precision of the resulting edge is rather limited.

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