Polymers for implantable devices exhibiting shape-memory effects

Abstract

The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed of materials (e.g., a coating) containing such compositions. The polymeric compositions can also contain at least one non-fouling moiety, at least additional biocompatible polymer, at least one biobeneficial material, at least one bioactive agent, or a combination thereof. The polymeric compositions are formulated to possess good mechanical, physical and biological properties. Moreover, implantable devices formed of materials comprising such compositions can be delivered to the treatment site in a conveniently compressed size and then can expand to dimensions appropriate for their medical functions.

Description

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AI Technical Summary

Benefits of technology

The invention is about creating biodegradable materials that can remember their original shape and change it after being implanted in the body. These materials can be used to make medical devices that can act as scaffolds, promote tissue regeneration, and deliver drugs locally. The materials have good strength, flexibility, and can be controlled to release drugs at specific rates. They can also stick to metal surfaces and are compatible with the body. The properties of the materials can be adjusted by changing the components and arrangement of the monomers used to make them.

Problems solved by technology

This patent discusses how creating a compressible device like a stent could help treat various medical needs without causing complications like inflammation or allergic reactions. These issues may occur when using traditional non-biodegradable materials. However, this new technology uses biodegradable polymeric materials that remember their original shapes and can change them based on environmental factors. By doing so, these materials can better adapt to different situations within the body and potentially improve patient outcomes while reducing risks related to current drugs delivered through stents.