6-Aminomorphinane Derivatives, Method for the Production and Use Thereof

a technology of aminomorphinane and derivatives, applied in the field of6aminomorphinane derivatives, can solve the problems of significant disadvantages of treatment, risks such as bleeding, infections or cartilage damage, and injections into affected tissue or joints, and achieves the effects of reducing side effects and toxicity, reducing the risk of bleeding, and prolonging the analgesic effect period
US20090209570A1Inactive Publication Date: 2009-08-20CHIRONWELLS
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
CHIRONWELLS
Publication Date
2009-08-20
Estimated Expiration
Not applicable · inactive patent

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Abstract

This invention relates to compounds of the formula (I).
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Description

PRIORITY CLAIM

[0001] This is a continuation of U.S. application Ser. No. 10 / 499,133, filed Jun. 17, 2004, which is a U.S. national stage of PCT International Application No. PCT / EP02 / 14343, filed Dec. 16, 2002, which claims priority of German Application No. 101 61 963.4, filed Dec. 17, 2001. The contents of these applications in their entirety are incorporated herein by reference.BACKGROUND OF THE INVENTION

[0002] This invention relates to a class of 6-amino-morphinan compounds which can be used as highly active analgesics. This invention also relates to their pharmaceutically acceptable salts and easily accessible derivatives (e.g. esters or amides of the amino acid derivatives), to a process for their manufacture and their application in the manufacture of pharmaceutical specialities.

[0003] The existence of opioid receptors as receptors of the central nervous system (CNS), which transfer an analgesic effect, has been clearly proven. These receptors are subdivided into three subtypes,...

Claims

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