Methods For Treating Baldness And Promoting Hair Growth

Abstract

The invention relates to methods of treating baldness, treating alopecia, promoting hair growth, and / or promoting hair follicle development and / or activation or stimulation on an area of the skin of a subject (for example, a human) by subjecting said area of the skin to integumental perturbation. Integumental perturbation can be used in combination with other treatments for promoting hair growth. The invention provides devices for integumental perturbation for promoting hair growth, and provides pharmaceutical compositions for use in combination with integumental perturbation for promoting hair growth.

Description

[0001]This application claims priority to U.S. provisional application Ser. No. 61 / 420,282, filed Dec. 6, 2010, U.S. provisional application Ser. No. 61 / 453,919, filed Mar. 17, 2011, U.S. provisional application Ser. No. 61 / 453,902, filed Mar. 17, 2011, U.S. provisional application Ser. No. 61 / 478,689, filed Apr. 25, 2011, and U.S. provisional application Ser. No. 61 / 513,906, filed Aug. 1, 2011, the entire contents of each of which is incorporated herein by reference in its entirety.1. INTRODUCTION[0002]The invention relates to methods of treating baldness, treating alopecia, promoting hair growth, and / or promoting hair follicle development and / or activation on an area of the skin of a subject (for example, a human) by subjecting said area of the skin to integumental perturbation. Integumental perturbation can be used in combination with other treatments for promoting hair growth. The invention provides devices for integumental perturbation for promoting hair growth, and provides ph...

AI Technical Summary

Benefits of technology

The patent describes a method for promoting the growth of hair on a subject by using integumental perturbation, which involves removing a portion of the skin. The method can involve using a non-occlusive pharmaceutical composition containing a hair growth-promoting agent. The method results in an increase in the amount of hair on the treated area of skin. The method can also involve removing the epithelium and / or the stratum corneum, resulting in a rougher surface appearance. The method can be performed using chemical treatments, mechanical or electromagnetic treatments, or a combination of these. Overall, the method provides a way to promote the growth of hair on a subject by disrupting the skin and promoting the transition of vellus hair to terminal hair.

Problems solved by technology

In certain aspects, a method provided herein for using integumental perturbation to promote the growth of hair results in an increase in the amount or thickness of hair on an area of skin of a subject.

In certain aspects, a method provided herein for using integumental perturbation to promote the growth of hair results in an increase of vellus hair on an area of skin of a subject.

Thus, in certain aspects, the integumental perturbation method causes only superficial wounding to the area of skin on which hair growth is desired.

Perturbing to the deeper papillary dermis results in more bleeding and the treated surface appears rougher.

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