A pharmaceutical composition for prenatal and postnatal care, preventing birth defects and improving memory, the composition includes Atractylodes macrocephala, vitamin A, β-carotene, complex vitamin B, vitamin C, vitamin D, vitamin E and macroelements calcium, magnesium and Trace elements zinc, selenium, iron, chromium, copper, molybdenum, and manganese are mainly suitable for pre-pregnancy women, pregnant women, and lactating mothers. They are very effective in preventing birth defects and improving memory, and at the same time have the effect of health care and tonic, and even long-term administration There will be no side effects either.