The invention discloses a preparation process of traditional Chinese medicine pills for treating urinary calculi. The process comprises the following steps: crushing lygodium japonicum, endothelium corneum gigeriae galli, rhizoma alismatis, agilawood, amber, semen plantaginis, radix curcumae, poria cocos, platycodon grandiflorum and radix cyathulae, performing sieving to obtain a mixed medicine powder, mixing lumbricus, scouring rush, chingma abutilon seed and liquorice, adding water, performing decocting for three times, combining decoctions, performing filtering to obtain filtrate, cooling the filtrate, adding potassium nitrate, performing uniform stirring to completely dissolve the potassium nitrate, performing filtering, heating and concentrating to obtain a concentrated solution, putting the mixed medicine powder, talcum powder, cane sugar and the concentrated solution into pill production equipment, and performing uniform mixing to prepare pills, thereby obtaining the traditionalChinese medicine pills for treating urinary calculi. The traditional Chinese medicine pills are prepared from sixteen Chinese herbal medicines and the cane sugar, treats urinary calculi by utilizingthe comprehensive synergistic effect of the sixteen Chinese herbal medicines, has small side effects on a human body, does not need to be decocted by a patient, and has the characteristics of simple and convenient treatment method, low price, remarkable curative effect and no pain in the treatment process.