The invention discloses a pre-operation hand cleaning and disinfecting device which comprises a square frame, tetrahedron sponge blocks, conveying net belts, transmission rollers, spiral sponge sleeves, a rectangular hole, a disinfectant bottle, electric adjusting valves, a water pump, a water purifier, an air blower, a cylinder, an alcohol bottle, a silica gel heating piece, an air guide pipe, awater drain pipe, rotating rods, first motors, a protection cover, linear motors, second motors, round rods, through holes, bearings, sliding grooves and slider . The device is compact in structure, conducive to comprehensively cleaning and disinfecting hands, good in cleaning effect, convenient for control disinfectant and water output and conducive to drying the hands through volatile gas with alcohol and hot air and realizes effect of reasonably saving disinfectant and water; by starting the water pump, the first motor and the second motor at the same time, the device is conducive to driving the spiral sponge sleeve and the conveying net belt to rotate for running and convenient for spraying the disinfectant in the disinfectant bottle on the hands and realizes effect of comprehensivelydisinfecting and cleaning the hands.