The application provides application of
nervonic acid in preparation of a product for promoting
hair regeneration, and relates to the biological field. The application of
nervonic acid in preparation of the product for promoting
hair regeneration includes that the concentration of the
nervonic acid in the product is 3%-10%, at least one of the following is included in promoting
hair regeneration: activating Wnt
signal pathway in
hair follicle stem cells, promoting expression of beta-
catenin, LEF1 and PCNA, and further including promoting
hair follicle organoid development
in vitro and improving
hair follicle regeneration capacity. It is found that the nervonic acid can act on the
hair follicle stem cells, effectively promotes the hair
follicle from the resting phase to the
growth phase by activating the Wnt / beta-
catenin and other regeneration pathways, and up-regulating the expression of PCNA, LEF1 and other proliferation-
related factors, and promotes hair regeneration. The technology retains the high efficiency and safety of the nervonic acid regulation, further expands the new application scene of the nervonic acid in the field of hair regeneration, and has significant conversion value and broad market prospect in the field of
clinical treatment of alopecia.