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Medicine composition for treating soft tissue damage and osteoarthropathy and its prepn process

A technology for soft tissue injury and osteoarthritis, which is applied in the field of symptomatic pharmaceutical compositions, can solve problems such as inability to arrange production, poor air permeability, black and thick paste, and achieves easy cleaning, promotion of blood spot absorption, and paste. delicate effect

Inactive Publication Date: 2007-12-12
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional Chinese medicine for the treatment of soft tissue injuries and bone and joint lesions in the Department of Orthopedics and Traumatology is mainly in the form of black plasters. Heavy metals such as lead red are used in production, which pollutes the environment. In recent years, it has been impossible to arrange production
The rubber plaster made in recent years uses gasoline as a solvent during production, which is explosive and requires an explosion-proof workshop for production, which also pollutes the environment. It has poor air permeability during application and often causes allergies
Other existing external dosage forms also have the disadvantages of black and thick paste, difficult to spread, pollute clothes, and difficult to clean

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0132] Embodiment 1: the preparation method of the external use ointment of pharmaceutical composition of the present invention:

[0133] a) Take 25g Panax notoginseng, 25g Polygonum cuspidatum, 20g Aconitum, 20g Araceae, 16g Duhuo, 10g Angelica, 10g Dipsacus, 10g dried ginger, 10g pepper, 10g clove basil oil, 16g turpentine oil, 26g menthol, 13g camphor, Borneol 13g is a total of fourteen raw materials. Take lovage, angelica, and dried ginger among them, grind them into 20-mesh coarse powder, use 6 to 8 times the amount of 80% ethanol as a solvent, and soak them for 24 hours. Speed ​​percolation, collect 1 to 3 times the amount of the initial eluent, store in another container, continue percolating, collect the secondary eluate, concentrate the secondary eluate below 60°C to a thick paste, add the initial eluent, and dilute with 80% ethanol to 3 times the amount to obtain the ethanol extract, and put it in a clean container for later use;

[0134] b) Take Polygonum cuspidatu...

Embodiment 2

[0139] Embodiment 2: Preparation of the pharmaceutical composition aerosol of the present invention:

[0140] a) Take 25g Panax notoginseng, 25g Polygonum cuspidatum, 20g Aconitum, 20g Araceae, 16g Duhuo, 10g Angelica, 10g Dipsacus, 10g dried ginger, 10g pepper, 10g clove basil oil, 16g turpentine oil, 26g menthol, 13g camphor, Borneol 13g is a total of fourteen raw materials. Take lovage, angelica, and dried ginger among them, grind them into 40-mesh coarse powder, use 6-8 times the amount of 80% ethanol as a solvent, and soak them for 24 hours. Speed ​​percolation, collect 1 to 3 times the amount of the initial eluent, store in another container, continue percolating, collect the secondary eluate, concentrate the secondary eluate below 60°C to a thick paste, add the initial eluent, and dilute with 80% ethanol to 3 times the amount to obtain the ethanol extract, and put it in a clean container for later use;

[0141] b) Take Polygonum cuspidatum, Panax notoginseng, Araceae, ...

Embodiment 3

[0146] Embodiment 3: the preparation of pharmaceutical composition liniment of the present invention:

[0147] a) Take 25g Panax notoginseng, 25g Polygonum cuspidatum, 20g Aconitum, 20g Araceae, 16g Duhuo, 10g Angelica, 10g Dipsacus, 10g dried ginger, 10g pepper, 10g clove basil oil, 16g turpentine oil, 26g menthol, 13g camphor, Borneol 13g has fourteen raw materials in total. Take lovage, angelica, and dried ginger among them, grind them into a 60-mesh coarse powder, use 6-8 times the amount of 80% ethanol as a solvent, and soak it for 24 hours. Speed ​​percolation, collect 1 to 3 times the amount of the initial eluent, store in another container, continue percolating, collect the secondary eluate, concentrate the secondary eluate below 60°C to a thick paste, add the initial eluent, and dilute with 80% ethanol to 3 times the amount to obtain the ethanol extract, and put it in a clean container for later use;

[0148] b) Take Polygonum cuspidatum, Panax notoginseng, Araceae, ...

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PUM

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Abstract

The medicine composition is prepared with 14 kinds of Chinese medicinal materials, including notoginseng, giant knotweed, aconite root, arisaema tuber, pubescent angelica root, etc. in certain weight proportion. The medicine composition and its preparation have the functions of promoting blood circulation to disperse blood clots, relaxing the muscles and joints, eliminating swelling, relieving pain, etc. and are used in treating soft tissue damage, osteoarthropathy, etc. The prepared medicine is yellowish semi-solid with scent, fine ointment, easy painting, easy cleaning and no contamination to clothing.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating swelling and pain and a preparation method thereof. Background technique [0002] Soft tissue injuries and bone and joint lesions in orthopedics and traumatology are often characterized by local swelling and pain. They are common pain syndromes in traditional Chinese medicine. Happens often in life. With the rapid development of transportation, construction, and industrial and mining industries, people's pace of life has accelerated, the incidence of various sprains, fractures, and dislocations has increased year by year, and the number of soft tissue injuries has increased. According to statistics, the number of patients with soft tissue injuries increases at a rate of 6-9% per year, causing huge economic losses to patients and the country. Therefore, patients have an urgent need for drugs for soft tissue injuries. [0003] Traditional Chinese medicine for the treatment of soft tiss...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K36/8884A61K36/81A61K36/714A61K36/704A61K36/54A61K36/534A61K36/53A61K36/258A61K36/232A61K36/185A61K36/15A61K31/125A61P19/02A61P19/00
Inventor 苏子仁周南平曾惠芳叶木荣赖小平黄琳
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE