Liquid level stabilizing device in micro-analysis chip liquid pool and method of use thereof

A technology of liquid level stabilization and micro-analysis, which is applied in the direction of analyzing materials, measuring devices, and material analysis through electromagnetic means, so as to achieve the effects of hydraulic pressure, liquid level stability, and wide application

Inactive Publication Date: 2008-05-21
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method is suitable for keeping the liquid level in the liquid storage tank stable when there is a liquid flow into the liquid storage tank; it is not applicable to the liquid storage tank with a simple liquid flow out

Method used

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  • Liquid level stabilizing device in micro-analysis chip liquid pool and method of use thereof
  • Liquid level stabilizing device in micro-analysis chip liquid pool and method of use thereof
  • Liquid level stabilizing device in micro-analysis chip liquid pool and method of use thereof

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Experimental program
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Embodiment 1

[0029] figure 1 . is a side sectional view of a preferred embodiment 1 according to the present invention. The micro-analysis chip is composed of upper (1) and lower (2) pieces, the upper (1) and lower (2) pieces are sealed by a bonding method, and a microchannel (3) is processed on the upper piece (1). Punch holes on the upper sheet (1) to form connecting channels (4). The chip is placed upright, and a horizontal channel (5) pipe is fixed directly on the surface of the upper chip (1) around the opening of the connection channel (4) to form a liquid storage pool. The liquid (6) in the liquid storage tank is communicated with the microchannel (3), and the phase interface of the liquid (6) in contact with the outside atmosphere—the vertical liquid surface (7) is arc-shaped.

Embodiment 2

[0031] figure 2 . is a side sectional view according to yet another preferred embodiment 2 of the present invention. The micro-analysis control chip consists of upper (1) and lower (2) pieces. The upper (1) and lower (2) sheets are sealed by a bonding method. Microchannels (3) are fabricated on the top sheet (1). Punch holes on the upper sheet (1) to form connecting channels (4). The chip is placed horizontally, and a horizontal channel (5) tube is fixed directly on the surface of the upper chip (1) around the opening of the connection channel (4) to form a liquid storage pool. The liquid (6) in the liquid storage tank is communicated with the microchannel (3), and the phase interface of the liquid (6) in contact with the outside atmosphere—the vertical liquid surface (7) is arc-shaped.

Embodiment 3

[0033] image 3 . is a side cross-sectional view of the liquid level stabilization micro-analysis chip of the overall system according to the preferred embodiment of the present invention. The micro-analysis chip consists of upper (1) and lower (2) pieces. The upper (1) and lower (2) sheets are sealed by a bonding method. Microchannels (3) are fabricated on the top sheet (1). A hole is punched at each end of the microchannel (3) on the upper sheet (1) to form a connecting channel (4). The chip is placed horizontally, directly on the surface of the upper chip (1), and a horizontal channel (5) tube is fixed around the mouth of the connection channel (4) to form a liquid storage pool. The liquid (6) in the liquid storage tank is communicated with the microchannel (3), and the phase interface of the liquid (6) in contact with the outside atmosphere—the vertical liquid surface (7) is arc-shaped. The two horizontal channels are on the same level.

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Abstract

The invention relates to an integrated level stabilizing device used to liquor storing pond on microanalysis chip and using method. Its character: the liquor storing pond is composed of linking channel and horizontal inlet or outlet channel with level stabilizing function. Its advantages: during analysis, when liquor flows in or out of the liquor storing pond in effective control time, it can keep the level constant in the liquor storing pond, so as to avoid the interference to chip analysis course because of level change.

Description

technical field [0001] The present invention relates to the field of microfluidic chip analysis, in particular to a liquid level stabilization device in a liquid storage tank of a microanalysis chip and a method of using the same. Background technique [0002] Usually, a micro-analysis chip is composed of upper and lower layers or multiple layers of chips, and the material of the chip is monocrystalline silicon, or quartz, or glass, or high molecular polymer. The area of ​​the chip is about a few square centimeters, the width and depth of the microchannel are micrometers, and it is generally a closed microchannel network. [0003] This patent relates to a reservoir system on a micro-analytical chip. Current on-chip reservoirs, literature (Manz A, Fettinger J C, Verpoorte E, Ludi H, Widmer H M, Harrison D J, Trend in Anal. Chem., 1991, 10:144) (Harrison D J, Manz A, Fan Z , Ludi H, Widmer H M, Anal. Chem., 1992, 64: 1926) (Jacobson S C, Hergenroder R, Koutny LB, Warmack R J...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N27/26G01N27/416G01N35/00C12Q1/68
Inventor 方群李丹妮陈宏黄艳贞方肇伦
Owner ZHEJIANG UNIV
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