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Chinese medicine preparation for treating ulcerative proctitis and its preparation process

A technology of ulcerative proctitis and traditional Chinese medicine preparations, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., which can solve the problems of gastrointestinal malabsorption, damage to the spleen and stomach, and decline

Inactive Publication Date: 2007-08-08
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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AI Technical Summary

Problems solved by technology

[0003]Treatment of ulcerative proctitis with traditional Chinese medicine oral preparations often has a decrease in drug efficacy due to gastrointestinal malabsorption and adverse irritation reactions that are easy to damage the spleen and stomach when some drugs are taken orally

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0033] 1. Compatibility of main ingredients (calculated based on 100% of the total amount of main ingredients)

[0034] (1)Bletilla striata 50% gallnut 20% Qingdai 20% borneol 10%

[0035] (2) Bletilla striata 40% gallnut 35% Qingdai 15% borneol 10%

[0036] (3) Bletilla striata 50% gallnut 30% Qingdai 10% borneol 10%

[0037] 2. Preparation method

[0038] One of the cases

[0039] 1) The preparation of the main ingredient: take 50% of Bletilla striata and add 25 times of water to extract, and then mix the Bletilla striata extract with 20% of Galla Chinensis, 20% of Qingdai and 10% of Borneolum Sanwei medicinal powder;

[0040] 2) Dissolve 100 grams of the main agent in 300 ml of glycerol solvent to make the main agent solution;

[0041] 3) Dissolve 200 grams of carboxymethyl cellulose in 500 ml of water to fully swell it, add 10 grams of chlorhexidine and 30 g of polyvinyl alcohol; mix the main agent solution in the above 2) step evenly, add water to 1000 ml, Stir evenl...

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PUM

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Abstract

The invention relates to a method for preparing the traditional medicines used to treat ulcerative proctitis, which is formed by the main drug formed by bletilla striata, gallnut, natural indigo and borneol, to be added with base medium, conservative, penetration accelerant, surface activator, solvent and water. And the preparation comprises that dissolving the main drug into solvent to prepare the main drug solution; adding water into medium to expand it, adding conservative and penetration accelerant to be mixed with the main drug solution, adding water to total amount, mixing uniformly, defoaming to obtain the gel agent, or defoaming, coating film, drying, removing the coat, slicing, preparing into film agent, while each ml gel agent or each film agent contains 0.1-300mg main drug. The inventive gel agent and film agent have small volume, low weight, simple storage, and high stability, while it can be fed via the endoscope in endoscope to improve the adsorption.

Description

1. Technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating ulcerative proctitis and a preparation method thereof. 2. Background technology [0002] Ulcerative proctitis is a clinically difficult disease. Western medicine currently lacks specific treatments and prescriptions. Western medicines that are effective for active patients are basically aminosalicylic acids and corticosteroids. Easy to relapse, many side effects of long-term medication and other problems. In recent years, scholars at home and abroad have carried out some studies on the treatment of this disease with cytokine monoclonal antibodies and antagonists, but they are still in the trial production stage. Therefore, finding more ideal and effective drugs with less side effects from the field of traditional Chinese medicine has become a research focus. Although there is no disease name of ulcerative pr...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/00A61K9/70A61K47/38A61P1/04A61P1/00A61K35/64A61K31/045
Inventor 陈红锦顾宁曾莉郭云飞钱海华陈邑岐曾艳高运军
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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