Method and apparatus for printing liquid droplets of biological molecules on substrate by utilizing charge concentration effect
A technology of biomolecules and charge concentration, applied in biochemical equipment and methods, microbial determination/inspection, printing, etc., can solve problems such as limiting device design
Inactive Publication Date: 2007-08-29
SAMSUNG ELECTRONICS CO LTD
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Problems solved by technology
The required distance between the first field-shaping electrode 4 and the second field-shaping electrode 7 limits the design of the device
Method used
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[0046] Hereinafter, the present invention will be described more fully with reference to the accompanying drawings, in which exemplary embodiments of the invention are shown.
[0047] 3 is a cross-sectional view of an apparatus 100 for printing biomolecular droplets or inks using charge concentration effects, according to one embodiment of the present invention. FIG. 4 is a plan view of the substrate 30 shown in FIG. 3 . 5 shows the distribution of positive charges in the electric field shaping electrode 20 and the negative charges induced by the positive charges, and the distribution of the biomolecular droplets 10 suspended at the outlet 23 when a voltage is applied to the printing device 100 of FIG. 3 . force. FIG. 6 shows a method of printing biomolecular droplets 10 using the device 100 of FIG. 3 . FIG. 7 shows the surface tension affecting the neck-shaped biomolecule droplet 10 when the biomolecule droplet 10 is dropped onto the substrate 30 in the printing device 100 ...
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Abstract
A device and method for printing biomolecules on a substrate uses an electric charge concentration effect. The device overcomes limitations of the material and surface characteristics of a substrate, enables accurate dropping of a biomolecular droplet onto a target surface of the substrate, prevents electric discharge, and thus allows the manufacturing of a high density biochip by depositing numerous biomolecular droplets, which are small in size and volume, onto a substrate. The device includes: a needle-shaped electric field forming electrode; a substrate which is grounded and disposed below the electric field forming electrode, the substrate including a target surface; and an open circuit type voltage applying unit which supplies first electric charges to the electric field forming electrode to drop the biomolecular droplet onto the target surface of the substrate.
Description
technical field [0001] The present invention relates to a device for printing biomolecular droplets on a substrate and a device for printing ink on a substrate or printing paper by using the electric charge concentration effect, and more particularly relates to a device for using the electric charge concentration effect to print biomolecules A device for printing biomolecular droplets of biomolecular materials such as nucleic acids (e.g., probes DNA, RNA, PNA and LNA), proteins (eg, antigens and antibodies), oligopeptides, eukaryotic cells (eg, human cells, animal cells, and plant cells), viruses, and bacteria, as well as a method that utilizes the charge concentration effect by dropping the ink A device that prints the contents of computer document files or picture files on printing paper, thereby printing ink on printing paper. Background technique [0002] As a development result of an epoch-making human genome project, human beings need methods for quickly providing a l...
Claims
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IPC IPC(8): B41J2/06B41J2/14G01N33/50C12Q1/68
CPCB01J2219/00691B01J2219/00677B01J2219/00364B01L2400/027B01J2219/00743B01J2219/00725B01L2300/0838B01J2219/00722B01L3/0262B01J2219/00612B01J2219/0061B01J2219/00689B01J2219/00585B01J2219/00659B01J2219/00497B01J2219/00574B01J2219/00596B01J2219/00637B01J2219/00605B01J19/0046B01J2219/00527B01J2219/00729B01J2219/00686
Inventor 李廷健赵慧贞许楠姜仁锡李凡石
Owner SAMSUNG ELECTRONICS CO LTD