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Rapamycins coating catheter

A technology of rapamycin and urinary catheters, applied in the field of urinary catheters, can solve the problems of high recurrence rate of stenosis

Inactive Publication Date: 2007-10-24
THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0002] Clinically, urethral stricture caused by urethral injury is very common. The treatment of the latter is endoscopic urethral incision or open surgery (resection of the stricture segment of the urethra + urethral anastomosis), and routine indwelling catheter, but the stricture recurs after the operation Therefore, urethral stricture has always been a difficult disease to treat in urology.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] As shown in FIG. 1 , it is a structural diagram of a double-chamber balloon catheter. The catheter includes an insertion end 1 for insertion into a patient's body, and a urination port 4 and a balloon valve 3 exposed outside the body. The urination port end 4 communicates with the catheter port 5 at the insertion end to discharge urine. There is also an air bag 2 at the insertion end to communicate with the air bag valve 3. After the catheter is inserted, gas or liquid is injected through the valve to expand the air bag 2 to prevent the catheter from coming off. Catheters are made of silicone, silicon gel, latex, or rubber. At the insertion end 1, especially at the part (outside of the balloon 2) that is placed in the urethra, a section of catheter outer surface with a length of 25 cm is coated with a rapamycin coating 10, and its dosage is such that it can exert an effective effect in the urethra. Biologically effective dose, that is, a dose that is effective in inhib...

Embodiment 2

[0015] As shown in Figure 2, it is a three-chamber balloon catheter, or commonly known as Foley's catheter. There is an air bag 2 and catheter openings 5, 7 at the insertion end 1, and three branches 3, 4, 6 at the other end. The urination port end 4 communicates with the catheterization port 5 at the insertion end, the urination port end 6 communicates with the catheterization port 7 at the insertion end, and the air bag 2 communicates with the air bag valve 3 . A rapamycin coating 10 is coated on the surface of the insertion end, especially a section with a length of 25 cm for indwelling in the urethra.

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Abstract

The invention discloses a catheter coated with rapamycin. The outer surface of part catheter is coated with catheter. It is used for preventing disease recurrence for urine injured patient or urethral stricture patient.

Description

technical field [0001] The invention relates to a medical product, in particular to a urinary catheter. Background technique [0002] Clinically, urethral stricture caused by urethral injury is very common. The treatment of the latter is endoscopic urethral incision or open surgery (resection of the stricture segment of the urethra + urethral anastomosis), and routine indwelling catheter, but the stricture recurs after the operation Therefore, urethral stricture has always been a difficult disease to treat in urology. Contents of the invention [0003] The object of the present invention is to provide a urinary catheter, which can significantly reduce the incidence rate of urethral stricture and the recurrence rate of urethral stricture by indwelling the treated catheter in the urethra of the patient. [0004] The present invention adopts the following technical scheme: a rapamycin-coated urinary catheter, characterized in that: the outer surface of the catheter at least ...

Claims

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Application Information

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IPC IPC(8): A61M25/00A61K31/436A61P13/02
Inventor 王平贤张艮甫黄赤兵范明齐冯嘉瑜肖亚方针强贾维胜
Owner THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV
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