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Method and device for analyzing amniotic fluid

A technology for amniotic fluid and data analysis, applied in the field of determining one or more biomarkers and monitoring the mother's health status, which can solve the problems of missed diagnosis of GDM

Inactive Publication Date: 2007-10-24
MCGILL UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, some studies acknowledge that selective screening based on these criteria may still miss the diagnosis of GDM

Method used

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  • Method and device for analyzing amniotic fluid
  • Method and device for analyzing amniotic fluid
  • Method and device for analyzing amniotic fluid

Examples

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no. 1 example

[0037] The first embodiment - NIR Raman spectroscopic analysis of amniotic fluid in vitro and its relationship with human birth weight

[0038]One embodiment of the present invention mainly uses Raman spectroscopy to identify a group of amniotic fluid biochemical markers that can predict the birth weight of infants. The advantages of our method are: (1) The method requires only a small (μl) sample of amniotic fluid to measure all important biochemical components simultaneously, thereby maintaining the chemical identity of these chemical components in the amniotic fluid fluid matrix which is important, The amniotic fluid matrix is ​​an important barometer of fetal health, because too little amniotic fluid (oligiohydramniois) or polyhydramnios (polyhydramniois) will threaten fetal health. This method overcomes the limitations of other chemical techniques that require separate analysis of components, since these techniques are not only affected by differences in concentration if ...

no. 3 example

[0079] Second and Third Embodiments - In Situ Detectors Including Optical Spectrometers

[0080] In a second example, intravaginal spectroscopy is used during routine ultrasound examinations (2-5 times) during pregnancy. Early detection can provide an opportunity for therapeutic or nutritional intervention. However, the thickness of cervical tissue (approximately 4mm) reduces the sensitivity of early pregnancy detection. On the contrary, due to the gradual thinning of the uterus during pregnancy, the intravaginal detection time will be delayed, and the interference of cervical tissue will be less, but the chance of medical intervention will be correspondingly reduced. We know that the use of ultrasound images of the amniotic sac can determine or guide the positioning of the probe, so that the detection of amniotic fluid will not interfere with the fetus. An optical spectrometer can also be integrated into the ultrasound intravaginal probe if desired.

[0081] The spectral r...

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Abstract

To increase cooling efficiency in an electronic cooling device for cooling equipment having an electrical heating element, and to simplify installation to a substrate having an object to be cooled. The electronic cooling device comprises: a thermoelectric module 10 having a endothermic surface 10a and a heat radiation surface 10b; a heat radiation member 20 thermally connected to the heat radiation surface 10b; a heat-conducting member 30 whose one surface is thermally connected to the endothermic surface 10a and the other is thermally connected to the object 40 to be cooled; and an engagement member 50 that fixes the object 40 to be cooled and the heat-conducting member 30 and is mounted to the heat-conducting member 30. In this manner, penetration by heat transfer from the heat radiation member 20 is prevented to fix the engagement member 50 and the substrate 45 for retaining the object 40 to be cooled, thus increasing the cooling efficiency. Additionally, the object 40 to be cooled can be adhered to the heat-conducting member 30 even for the object 40 to be cooled, where the through hole cannot be opened from the rear.

Description

[0001] related application [0002] This application claims priority to US Provisional Patent Application No. 60 / 496,884, filed August 21, 2003, the contents of which are hereby incorporated by reference. [0003] U.S. federally funded research projects [0004] The invention disclosed and claimed in this application is not a research project funded by the U.S. federal government or its agencies, and the U.S. government does not have the right to apply for this patent. technical field [0005] The present invention relates to methods and devices for determining a fetal health condition or a risk of a fetal health condition. The invention also relates to methods and devices for monitoring the health of a mother. The invention further relates to methods and devices for determining one or more biomarkers by analyzing amniotic fluid. Background technique [0006] Assessment of fetal birth weight is an important part of prenatal care. Therefore, accurate determination of feta...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B8/00
CPCA61B5/7275
Inventor K·G·科斯基D·H·伯恩斯
Owner MCGILL UNIV
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